INT7297

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.45
First Reported 1984
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 8
Total Number 10
Disease Relevance 5.33
Pain Relevance 0.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (NPPA) nucleus (NPPA) cytoplasm (NPPA)
Anatomy Link Frequency
muscle 3
NPPA (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 1 96.76 Very High Very High Very High
Cholecystokinin 1 96.28 Very High Very High Very High
Dynorphin 1 95.60 Very High Very High Very High
bradykinin 1 95.08 Very High Very High Very High
substance P 1 94.60 High High
tetrodotoxin 6 81.40 Quite High
agonist 9 78.72 Quite High
antagonist 5 75.00 Quite High
anesthesia 3 25.00 Low Low
withdrawal 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Natriuresis 70 100.00 Very High Very High Very High
Heart Rate Under Development 21 96.16 Very High Very High Very High
Pressure And Volume Under Development 6 92.28 High High
Appetite Loss 12 76.32 Quite High
Obesity 66 56.80 Quite High
Insulin Resistance 6 53.12 Quite High
Diuresis 1 39.60 Quite Low
Hypotension 2 38.32 Quite Low
Hyperglycemia 3 29.80 Quite Low
Hyperinsulinism 3 29.08 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Natriuretic peptides have been demonstrated to cause relaxation of the human gallbladder muscle through interaction with natriuretic peptide receptor-B (NPR-B/NPR2).
natriuretic peptide Binding (interaction) of in muscle associated with natriuresis
1) Confidence 0.45 Published 2008 Journal Regul. Pept. Section Abstract Doc Link 17920706 Disease Relevance 0.75 Pain Relevance 0.03
Natriuretic peptides cause relaxation of human and guinea-pig gallbladder muscle through interaction with natriuretic peptide receptor-B.
natriuretic peptide Binding (interaction) of in muscle associated with natriuresis
2) Confidence 0.43 Published 2005 Journal Regul. Pept. Section Title Doc Link 15927695 Disease Relevance 0.79 Pain Relevance 0.16
Our findings may also be important in terms of human pathophysiology, both in conditions associated with increased ANP and with decreased ANP availability.
ANP Binding (associated) of
3) Confidence 0.34 Published 2008 Journal Diabetes Section Body Doc Link PMC2584124 Disease Relevance 0.98 Pain Relevance 0
Our findings may also be important in terms of human pathophysiology, both in conditions associated with increased ANP and with decreased ANP availability.
ANP Binding (associated) of
4) Confidence 0.34 Published 2008 Journal Diabetes Section Body Doc Link PMC2584124 Disease Relevance 0.96 Pain Relevance 0
HS-142-1, a novel polysaccharide, isolated from the culture broth of Aureobasidium pullulans var. melanigenum, has been found to inhibit selectively the binding of [125I]atrial natriuretic peptide (ANP) to the guanylyl cyclase-linked ANP receptor (ANP-B receptor) and production of cyclic GMP by ANP.
ANP Binding (binding) of associated with natriuresis
5) Confidence 0.33 Published 1992 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 1346647 Disease Relevance 0.41 Pain Relevance 0.04
HS-142-1, a novel polysaccharide, isolated from the culture broth of Aureobasidium pullulans var. melanigenum, has been found to inhibit selectively the binding of [125I]atrial natriuretic peptide (ANP) to the guanylyl cyclase-linked ANP receptor (ANP-B receptor) and production of cyclic GMP by ANP.
ANP Binding (binding) of associated with natriuresis
6) Confidence 0.33 Published 1992 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 1346647 Disease Relevance 0.41 Pain Relevance 0.04
Taken together, these results demonstrate that natriuretic peptides cause relaxation of human and guinea-pig gallbladder muscle through interaction with the natriuretic peptide receptor-B.
natriuretic peptide Binding (interaction) of in muscle associated with natriuresis
7) Confidence 0.33 Published 2005 Journal Regul. Pept. Section Abstract Doc Link 15927695 Disease Relevance 0.76 Pain Relevance 0.19
The antiserum recognizes atriopeptin I, atriopeptin III, and alpha-human atrial natriuretic polypeptide, but does not recognize met-enkephalin, cholecystokinin, dynorphin A, bradykinin, substance P, or beta-endorphin.
atriopeptin Binding (recognizes) of associated with natriuresis, dynorphin, enkephalin, bradykinin, cholecystokinin and substance p
8) Confidence 0.31 Published 1984 Journal Peptides Section Abstract Doc Link 6241672 Disease Relevance 0.10 Pain Relevance 0.29
In the postprandial phase, venous glucose concentration increased similarly with placebo or ANP, reaching a maximum ?
ANP Binding (placebo) of
9) Confidence 0.29 Published 2008 Journal Diabetes Section Body Doc Link PMC2584124 Disease Relevance 0 Pain Relevance 0
HS-142-1, a novel microbial product, blocked 125I-labeled rat atrial natriuretic peptide (rANP) (= ANF(99-126)) binding to bovine adrenocortical membranes, where guanylyl cyclase-containing receptors are predominantly expressed.
natriuretic peptide Binding (binding) of associated with natriuresis
10) Confidence 0.01 Published 1992 Journal Eur. J. Pharmacol. Section Abstract Doc Link 1355444 Disease Relevance 0.17 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox