INT72981

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Context Info
Confidence 0.45
First Reported 1997
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.05
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Scg2) extracellular region (Scg2) intracellular (Scg2)
Scg2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuropeptide 4 100.00 Very High Very High Very High
Enkephalin 3 100.00 Very High Very High Very High
bDMF 32 99.72 Very High Very High Very High
medulla 2 98.08 Very High Very High Very High
Catecholamine 3 91.72 High High
Inflammation 1 87.52 High High
spastic colon 1 67.84 Quite High
Lamotrigine 46 5.00 Very Low Very Low Very Low
depression 22 5.00 Very Low Very Low Very Low
carbamazepine 18 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 9 98.32 Very High Very High Very High
Convulsion 3 89.52 High High
Mucositis 1 88.16 High High
Thyroid Disease 2 79.12 Quite High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

1 68.04 Quite High
Functional Bowel Disorder 1 67.84 Quite High
Hypoglycemia 1 36.08 Quite Low
Manic Depressive Disorder 250 19.68 Low Low
Depression 28 5.00 Very Low Very Low Very Low
Recurrence 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Secretogranin II - the secretoneurin precursor - was induced by MD.
Positive_regulation (induced) of Secretogranin II
1) Confidence 0.45 Published 2008 Journal Journal of proteomics Section Abstract Doc Link 18541476 Disease Relevance 0.58 Pain Relevance 0.11
This treatment increased mRNA steady-state levels of enkephalin, neuropeptide Y and chromogranin B 2-6-fold.
Positive_regulation (increased) of chromogranin B 2-6-fold associated with neuropeptide and enkephalin
2) Confidence 0.35 Published 1997 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 9427505 Disease Relevance 0.24 Pain Relevance 0.50
Among these, lithium upregulated the period homolog 2 (Per2), the secretogranin II (Scg2), the BDNF and the IMPA1 genes.
Positive_regulation (upregulated) of secretogranin II associated with bdmf
3) Confidence 0.33 Published 2010 Journal Human Genomics and Proteomics : HGP Section Body Doc Link PMC2958627 Disease Relevance 0.08 Pain Relevance 0.05
Among these, lithium upregulated the period homolog 2 (Per2), the secretogranin II (Scg2), the BDNF and the IMPA1 genes.
Positive_regulation (upregulated) of Scg2 associated with bdmf
4) Confidence 0.24 Published 2010 Journal Human Genomics and Proteomics : HGP Section Body Doc Link PMC2958627 Disease Relevance 0.08 Pain Relevance 0.05

General Comments

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