INT73028

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Context Info
Confidence 0.55
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 3
Disease Relevance 1.53
Pain Relevance 2.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Ctsb) mitochondrion (Ctsb) extracellular space (Ctsb)
extracellular region (Ctsb) response to stress (Ctsb) lysosome (Ctsb)
Ctsb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 30 99.98 Very High Very High Very High
Disease Link Frequency Relevance Heat
Apoptosis 18 100.00 Very High Very High Very High
Death 3 98.52 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Morphine induces splenocyte apoptosis and enhanced mRNA expression of cathepsin-B.
Positive_regulation (enhanced) of Transcription (expression) of cathepsin-B associated with apoptosis and morphine
1) Confidence 0.55 Published 1997 Journal Inflammation Section Title Doc Link 9429908 Disease Relevance 0.52 Pain Relevance 0.85
Splenocytes from morphine treated rats also showed increased mRNA expression of cathepsin-B, a gene associated with active cell death.
Positive_regulation (increased) of Transcription (expression) of cathepsin-B associated with death and morphine
2) Confidence 0.39 Published 1997 Journal Inflammation Section Abstract Doc Link 9429908 Disease Relevance 0.50 Pain Relevance 0.84
Morphine induces splenocyte apoptosis and enhanced mRNA expression of cathepsin-B.
Positive_regulation (induces) of Transcription (expression) of cathepsin-B associated with apoptosis and morphine
3) Confidence 0.39 Published 1997 Journal Inflammation Section Title Doc Link 9429908 Disease Relevance 0.52 Pain Relevance 0.85

General Comments

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