INT73145

Context Info Confidence 0.07 First Reported 1997 Last Reported 1999 Negated 0 Speculated 0 Reported most in Abstract Documents 2 Total Number 2 Disease Relevance 0.17 Pain Relevance 0.36

extracellular space (Abp1) oxidoreductase activity (Abp1) extracellular region (Abp1) plasma membrane (Abp1) biological_process (Abp1)

Anatomy Link Frequency brain 1 Abp1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat monoamine 1 99.74 Bioavailability 1 97.20 Clonidine 1 95.96 carbamazepine 1 90.28 Central nervous system 1 79.12 Paracetamol 1 78.88

Disease Link Frequency Relevance Heat Toxicity 1 91.64 Hepatotoxicity 1 76.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Inhibition of monoamine oxidase and histaminase by isoniazid can cause significant drug-food interactions.

histaminase Binding (interactions) of associated with monoamine

1) Confidence 0.07 Published 1999 Journal Am. J. Med. Sci. Section Abstract Doc Link 10334118 Disease Relevance 0.17 Pain Relevance 0.22

AGM is synthetized in brain from arginine decarboxylase, and metabolized by diamine oxidase.

diamine oxidase Binding (metabolized) of in brain

2) Confidence 0.01 Published 1997 Journal Pol J Pharmacol Section Abstract Doc Link 9437754 Disease Relevance 0 Pain Relevance 0.14

General Comments

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