INT73156

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Context Info
Confidence 0.48
First Reported 1997
Last Reported 2003
Negated 2
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.23
Pain Relevance 1.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
nucleus 2
CPP (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 9 100.00 Very High Very High Very High
amygdala 1 99.36 Very High Very High Very High
Dopamine 6 98.04 Very High Very High Very High
Nucleus accumbens 2 94.88 High High
Central grey 3 81.88 Quite High
agonist 1 69.60 Quite High
isoflurane 2 50.00 Quite Low
cva 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 3 81.88 Quite High
Cv General 3 Under Development 3 16.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Lesions of the mesolimbic dopamine system, the ventral pallidum, the lateral nucleus of the amygdala, or the caudate putamen had no effect on a morphine-induced CPP.
Neg (no) Regulation (effect) of Positive_regulation (induced) of CPP in nucleus associated with dopamine, amygdala and morphine
1) Confidence 0.48 Published 1997 Journal Behav. Neurosci. Section Abstract Doc Link 9438800 Disease Relevance 0.23 Pain Relevance 0.77
We have previously shown that diazepam blocks both the formation and the expression of amphetamine-induced conditioned place preference (CPP), but has no effect on the CPP induced by morphine.
Neg (no) Regulation (effect) of Positive_regulation (induced) of CPP associated with morphine
2) Confidence 0.20 Published 2000 Journal Neuroreport Section Abstract Doc Link 10943721 Disease Relevance 0 Pain Relevance 0.43
The effect of MAP on CPP is 3-4 times higher than the effect of the increases in ICP on CPP and this makes MAP the most important factor in preserving CPP.
Regulation (effect) of Positive_regulation (increases) of CPP
3) Confidence 0.17 Published 2003 Journal Acta Anaesthesiol Scand Section Body Doc Link 12904183 Disease Relevance 0 Pain Relevance 0

General Comments

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