INT73240

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Context Info
Confidence 0.41
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IFNG) extracellular region (IFNG)
Anatomy Link Frequency
mononuclear cells 2
IFNG (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 9 97.50 Very High Very High Very High
Neuritis 10 95.08 Very High Very High Very High
Inflammation 2 28.00 Quite Low
Disease Link Frequency Relevance Heat
Cancer 1 100.00 Very High Very High Very High
Necrosis 1 100.00 Very High Very High Very High
Optic Neuritis 10 95.08 Very High Very High Very High
Congenital Anomalies 2 85.76 High High
INFLAMMATION 2 28.00 Quite Low
Disease 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To study a possible relation between cytokine profiles and presence versus absence of MS-like brain MRI lesions and CSF OB, we used in situ hybridization to examine mRNA expression of the proinflammatory interleukin-12 (IL-12), interferon-gamma, and tumor necrosis factor-alpha and the immune response downregulating IL-10, transforming growth factor-beta, and IL-4 in blood and CSF mononuclear cells (MNC) from 59 patients with untreated ON.
Negative_regulation (downregulating) of Transcription (expression) of interferon-gamma in mononuclear cells associated with necrosis, cancer, neuritis and cytokine
1) Confidence 0.41 Published 1998 Journal Neurology Section Abstract Doc Link 9443483 Disease Relevance 0.92 Pain Relevance 0.76

General Comments

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