INT73377

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Context Info
Confidence 0.03
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.15
Pain Relevance 1.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Adarb1) intracellular (Adarb1) extracellular space (Npy)
extracellular region (Npy) RNA binding (Adarb1) nucleolus (Adarb1)
Anatomy Link Frequency
brain 1
cortex 1
Npy (Rattus norvegicus)
Adarb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 8 99.20 Very High Very High Very High
antagonist 7 87.28 High High
fortral 8 85.24 High High
Neuropeptide 4 75.00 Quite High
Nucleus accumbens 3 75.00 Quite High
agonist 3 74.08 Quite High
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Psychosis 2 97.24 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our findings suggest a role for NPY, via sigma receptors, in the regulation of dopamine levels in areas of brain critical to psychosis and reinforcement.
NPY Regulation (role) of receptors in brain associated with dopamine and psychosis
1) Confidence 0.03 Published 1998 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 9454797 Disease Relevance 0.15 Pain Relevance 0.73
These findings suggest a role for NPY, via sigma receptors, as a modulator of dopamine levels in the prefrontal cortex.
NPY Regulation (role) of receptors in cortex associated with dopamine
2) Confidence 0.02 Published 1998 Journal Schizophr. Res. Section Abstract Doc Link 9633834 Disease Relevance 0 Pain Relevance 0.65

General Comments

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