INT73398

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Context Info
Confidence 0.10
First Reported 1997
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 1.27

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extracellular region (Pnoc) nucleus (Nr1d2) DNA binding (Nr1d2)
Pnoc (Rattus norvegicus)
Nr1d2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
orphanin 16 100.00 Very High Very High Very High
Dynorphin 8 100.00 Very High Very High Very High
opioid receptor 2 98.80 Very High Very High Very High
narcan 4 64.32 Quite High
Opioid 2 54.80 Quite High
Morphine 2 54.08 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nociceptin (orphanin FQ), a heptadecapeptide with some sequence homology to dynorphin A, has been proposed as an endogenous ligand for a previously cloned orphan receptor with significant homology to opioid receptors.
Nociceptin Binding (ligand) of orphan receptor associated with dynorphin, orphanin and opioid receptor
1) Confidence 0.10 Published 1997 Journal Eur. J. Pharmacol. Section Abstract Doc Link 9455999 Disease Relevance 0 Pain Relevance 0.63
Nociceptin (orphanin FQ), a heptadecapeptide with some sequence homology to dynorphin A, has been proposed as an endogenous ligand for a previously cloned orphan receptor with significant homology to opioid receptors.
orphanin FQ Binding (ligand) of orphan receptor associated with dynorphin, orphanin and opioid receptor
2) Confidence 0.10 Published 1997 Journal Eur. J. Pharmacol. Section Abstract Doc Link 9455999 Disease Relevance 0 Pain Relevance 0.63

General Comments

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