INT73492

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Context Info
Confidence 0.08
First Reported 1997
Last Reported 1997
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.11
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL4) extracellular region (IL4) plasma membrane (PTGER2)
signal transducer activity (PTGER2)
PTGER2 (Homo sapiens)
IL4 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 18 95.32 Very High Very High Very High
Inflammation 12 80.64 Quite High
Pain 2 62.28 Quite High
Disease Link Frequency Relevance Heat
Necrosis 2 98.60 Very High Very High Very High
Cancer 2 98.24 Very High Very High Very High
INFLAMMATION 12 80.64 Quite High
Fever 2 63.32 Quite High
Increased Venous Pressure Under Development 2 62.92 Quite High
Pain 2 62.28 Quite High
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus PGE2 does not act by increasing IL-4 production in priming cultures, and its effects are partly IL-4 independent and largely IL-2 independent.
PGE2 Positive_regulation (increasing) of Gene_expression (production) of IL-4
1) Confidence 0.08 Published 1997 Journal Eur. J. Immunol. Section Abstract Doc Link 9464843 Disease Relevance 0.35 Pain Relevance 0.35
PGE2 does not significantly increase IL-4 production in priming cultures, whereas it suppresses IL-2 and IFN-gamma.
PGE2 Neg (not) Positive_regulation (increase) of Gene_expression (production) of IL-4
2) Confidence 0.08 Published 1997 Journal Eur. J. Immunol. Section Abstract Doc Link 9464843 Disease Relevance 0.75 Pain Relevance 0.52

General Comments

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