INT7351

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Context Info
Confidence 0.58
First Reported 1987
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.87
Pain Relevance 0.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (NPS)
Anatomy Link Frequency
liver 1
NPS (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 4 97.36 Very High Very High Very High
Analgesic 9 97.28 Very High Very High Very High
alcohol 2 90.72 High High
Antinociceptive 3 87.84 High High
Inflammation 3 39.56 Quite Low
cva 9 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 8 97.40 Very High Very High Very High
Cirrhosis 16 92.56 High High
Hemorrhage 39 91.32 High High
Chlamydia Infection 1 83.92 Quite High
Dizziness 4 83.64 Quite High
Fatigue 4 83.12 Quite High
Pneumonia 1 83.12 Quite High
Cytomegalovirus Infection 1 82.32 Quite High
Gastrointestinal Hemorrhage 2 81.48 Quite High
Melena 2 80.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A series of diastereomeric dipeptides, analogues of the analgesic compound H-Lys-Trp(Nps)-OMe (2), containing 3,7-diamino-2-hydroxyheptanoic acid (DAHHA) and 2-[(o-nitrophenyl)sulfenyl]tryptophan [Trp(Nps)] has been synthesized.
Gene_expression (synthesized) of Nps associated with analgesic
1) Confidence 0.58 Published 1992 Journal J. Med. Chem. Section Abstract Doc Link 1347791 Disease Relevance 0 Pain Relevance 0.59
The syntheses of dipeptide derivatives of the general formula X-Trp(Nps)-OR (R = H or Me; X = Lys, Gly, Ala, Leu, Ser, Glu, His, Arg, Orn, Dpr, Gpr and Har) are described.
Gene_expression (syntheses) of Nps
2) Confidence 0.58 Published 1987 Journal Int. J. Pept. Protein Res. Section Abstract Doc Link 3610476 Disease Relevance 0 Pain Relevance 0.24
More recently, the NPS RADAR project has shown the way forward.
Gene_expression (project) of NPS RADAR
3) Confidence 0.56 Published 2005 Journal Aust New Zealand Health Policy Section Body Doc Link PMC548296 Disease Relevance 0 Pain Relevance 0
Therefore, reliable methods of isolating or producing uncalcified NPs must be developed.
Gene_expression (producing) of NPs
4) Confidence 0.53 Published 2008 Journal International Journal of Nanomedicine Section Body Doc Link PMC2527666 Disease Relevance 0.39 Pain Relevance 0
As the NPs caring for these patients we must also be vigilant at reducing further injury to the liver.
Gene_expression (caring) of NPs in liver associated with injury
5) Confidence 0.14 Published 2010 Journal Journal of the American Academy of Nurse Practitioners Section Body Doc Link PMC3017746 Disease Relevance 1.48 Pain Relevance 0.05

General Comments

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