INT73524

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Context Info
Confidence 0.27
First Reported 1998
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 4.82
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Ear1) cellular_component (Ear1) biological_process (Ear1)
nuclease activity (Ear1)
Anatomy Link Frequency
eosinophil 3
nasal 1
lung 1
Ear1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 34 97.00 Very High Very High Very High
headache 4 82.64 Quite High
alcohol 1 82.08 Quite High
anesthesia 8 77.44 Quite High
cytokine 24 73.76 Quite High
peripheral neuropathy 1 55.20 Quite High
chemokine 4 54.08 Quite High
methotrexate 10 19.20 Low Low
abdominal pain 1 9.00 Low Low
corticosteroid 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Eczema 11 99.64 Very High Very High Very High
Loss Of Sense Of Smell 2 99.46 Very High Very High Very High
Hypersensitivity 87 99.02 Very High Very High Very High
Disease 56 98.00 Very High Very High Very High
INFLAMMATION 35 97.00 Very High Very High Very High
Echinococcosis 10 96.84 Very High Very High Very High
Dyspnea 3 89.76 High High
Aspergillus Infection 3 87.80 High High
Asthma 33 87.40 High High
Rhinitis 12 86.44 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
[Evaluation of eosinophil cationic protein levels with clinical symptoms and laboratory findings of patients with cystic echinococcosis].
Positive_regulation ([Evaluation) of eosinophil cationic protein in eosinophil associated with echinococcosis
1) Confidence 0.27 Published 2009 Journal Mikrobiyol Bul Section Title Doc Link 19621614 Disease Relevance 0.74 Pain Relevance 0.05
Comparison of invasive and noninvasive lung function measurements of EAR
Positive_regulation (measurements) of EAR in lung
2) Confidence 0.10 Published 2005 Journal Respir Res Section Body Doc Link PMC1316879 Disease Relevance 0.26 Pain Relevance 0.08
With both methods, allergic mice, sensitized and boosted with A. fumigatus, elicited allergen-specific EAR to A. fumigatus (p < 0.05 versus controls).
Positive_regulation (elicited) of EAR associated with hypersensitivity
3) Confidence 0.09 Published 2005 Journal Respir Res Section Abstract Doc Link PMC1316879 Disease Relevance 0.49 Pain Relevance 0.04
During octenol exposure subjective ratings of smell and nasal irritation were increased together with higher nasal lavage biomarker levels of eosinophil cationic protein, myeloperoxidase and lysozyme.
Positive_regulation (increased) of eosinophil cationic protein in nasal associated with loss of sense of smell
4) Confidence 0.06 Published 2008 Journal Toxicol. Lett. Section Abstract Doc Link 18706986 Disease Relevance 0.43 Pain Relevance 0.18
Nonspecific inflammatory markers such as erythrocyte sedimentation rate, C-reactive protein, fibrinogen as well as eosinophil cationic protein (ECP) were also increased.
Positive_regulation (increased) of eosinophil cationic protein in eosinophil
5) Confidence 0.05 Published 1998 Journal Dtsch. Med. Wochenschr. Section Body Doc Link 9465849 Disease Relevance 0.17 Pain Relevance 0
Because of the limited availability of ECP, its high cost, and the lack of controlled trials, ECP is limited for patients who have failed glucocorticoid and other immunosuppressive therapies.
Positive_regulation (availability) of ECP
6) Confidence 0.03 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1936286 Disease Relevance 0.72 Pain Relevance 0.08
Eosinophil numbers as well as eosinophil granule protein levels in peripheral blood are elevated in most AD patients and appear to correlate with disease activity.
Positive_regulation (elevated) of eosinophil granule protein in Eosinophil associated with eczema and disease
7) Confidence 0.02 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2846745 Disease Relevance 2.01 Pain Relevance 0.11

General Comments

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