INT7367

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Context Info
Confidence 0.49
First Reported 1987
Last Reported 1996
Negated 0
Speculated 2
Reported most in Abstract
Documents 5
Total Number 8
Disease Relevance 1.55
Pain Relevance 2.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ghrh, Gh1) extracellular region (Ghrh, Gh1) cytosol (Gh1)
signal transduction (Gh1) mitochondrion (Gh1) plasma membrane (Gh1)
Anatomy Link Frequency
pituitary 4
median eminence 2
Ghrh (Rattus norvegicus)
Gh1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Somatostatin 22 100.00 Very High Very High Very High
Neuropeptide 2 98.68 Very High Very High Very High
Enkephalin 2 97.48 Very High Very High Very High
Endogenous opioid 1 95.32 Very High Very High Very High
anesthesia 5 94.72 High High
Opioid 3 87.80 High High
antagonist 4 76.56 Quite High
Central nervous system 1 72.92 Quite High
agonist 4 66.56 Quite High
fluoxetine 8 65.76 Quite High
Disease Link Frequency Relevance Heat
Reactive Attachment Disorder 2 99.20 Very High Very High Very High
Diabetes Mellitus 20 99.14 Very High Very High Very High
Immunization 4 97.92 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Growth hormone-releasing factor (GRF) and somatostatin (SS) provide opposing regulation of GH secretion, and both are modified by noradrenergic and serotonergic stimuli in neonatal and adult rats.
Growth hormone-releasing factor Regulation (regulation) of Localization (secretion) of GH associated with somatostatin
1) Confidence 0.49 Published 1996 Journal Psychoneuroendocrinology Section Abstract Doc Link 8774064 Disease Relevance 0.10 Pain Relevance 0.42
Growth hormone-releasing factor (GRF) and somatostatin (SS) provide opposing regulation of GH secretion, and both are modified by noradrenergic and serotonergic stimuli in neonatal and adult rats.
GRF Regulation (regulation) of Localization (secretion) of GH associated with somatostatin
2) Confidence 0.49 Published 1996 Journal Psychoneuroendocrinology Section Abstract Doc Link 8774064 Disease Relevance 0.10 Pain Relevance 0.42
Cognizant of the important stimulatory effects of growth hormone-releasing hormone (GHRH) on GH secretion, we sought to determine if this neuropeptide plays any role in mediating GH secretion in food-deprived rats.
growth hormone-releasing hormone Regulation (effects) of Localization (secretion) of GH associated with neuropeptide
3) Confidence 0.43 Published 1992 Journal Life Sci. Section Abstract Doc Link 1347904 Disease Relevance 0.17 Pain Relevance 0.33
Cognizant of the important stimulatory effects of growth hormone-releasing hormone (GHRH) on GH secretion, we sought to determine if this neuropeptide plays any role in mediating GH secretion in food-deprived rats.
GHRH Regulation (effects) of Localization (secretion) of GH associated with neuropeptide
4) Confidence 0.43 Published 1992 Journal Life Sci. Section Abstract Doc Link 1347904 Disease Relevance 0.17 Pain Relevance 0.33
Although KP-102 and GRF acted synergistically on GH secretion in control animals, they acted additively in cysteamine-administered rats.
GRF Regulation (acted) of Localization (secretion) of GH
5) Confidence 0.26 Published 1995 Journal Nippon Ika Daigaku Zasshi Section Abstract Doc Link 7775651 Disease Relevance 0 Pain Relevance 0
Moreover we have evaluated in intact male rats the effect of exogenous GH on median eminence (ME) GHRH stores and the ability of FK 33-824 to stimulate GH and prolactin (PRL) secretion and of exogenous GHRH to induce GH secretion.
GHRH Regulation (effect) of Localization (secretion) of GH in median eminence
6) Confidence 0.19 Published 1987 Journal J. Endocrinol. Invest. Section Abstract Doc Link 2957419 Disease Relevance 0 Pain Relevance 0.55
In order to determine whether there is an abnormality in the pituitary responsiveness to GRF in the diabetic rat, we examined the in vivo and in vitro effects of hGRF-44 NH2 (hGRF) on growth hormone (GH) release in the spontaneously diabetic BB Wistar rat.
hGRF Spec (examined) Regulation (effects) of Localization (release) of GH in pituitary associated with diabetes mellitus
7) Confidence 0.14 Published 1987 Journal Neuroendocrinology Section Abstract Doc Link 2888037 Disease Relevance 0.50 Pain Relevance 0.09
In order to determine whether there is an abnormality in the pituitary responsiveness to GRF in the diabetic rat, we examined the in vivo and in vitro effects of hGRF-44 NH2 (hGRF) on growth hormone (GH) release in the spontaneously diabetic BB Wistar rat.
hGRF Spec (examined) Regulation (effects) of Localization (release) of GH in pituitary associated with diabetes mellitus
8) Confidence 0.14 Published 1987 Journal Neuroendocrinology Section Abstract Doc Link 2888037 Disease Relevance 0.50 Pain Relevance 0.09

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