INT73675

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Context Info
Confidence 0.09
First Reported 1997
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 3.30
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il1f6) extracellular region (Il1f6) cellular_component (Il1f6)
Anatomy Link Frequency
brains 1
keratinocytes 1
Il1f6 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 29 98.86 Very High Very High Very High
anesthesia 1 76.16 Quite High
cytokine 10 68.72 Quite High
Inflammatory mediators 1 66.68 Quite High
Inflammatory response 5 64.80 Quite High
psoriasis 1 39.68 Quite Low
member 8 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 14 99.88 Very High Very High Very High
Viral Meningitis 8 99.76 Very High Very High Very High
Acanthosis 8 99.50 Very High Very High Very High
Cancer 1 98.92 Very High Very High Very High
INFLAMMATION 32 98.86 Very High Very High Very High
Necrosis 1 98.68 Very High Very High Very High
Severe Combined Immunodeficiency 6 97.16 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 6 95.52 Very High Very High Very High
Adhesions 4 95.36 Very High Very High Very High
Psoriasis 7 92.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The role of IL-1F8 in the induction of the hyperproliferative phenotype is consistent with the cutaneous inflammation, hyperkeratosis, and acanthosis seen in transgenic mice overexpressing IL-1F6 in keratinocytes (Blumberg et al., 2007).
Gene_expression (overexpressing) of IL-1F6 in keratinocytes associated with targeted disruption, inflammation and acanthosis
1) Confidence 0.09 Published 2010 Journal The Journal of Cell Biology Section Body Doc Link PMC2845079 Disease Relevance 0.96 Pain Relevance 0.22
The expression of interleukin-1 (IL-1 beta, IL-6, IL-10), tumor necrosis factors-alpha (TNF alpha), vascular endothelial growth factor (VEGF), and adhesion molecules (E-selectin, intracellular cell adhesion molecule (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1)) in encephalitic brains of mice and humans was evaluated by semi-quantitative polymerase chain reaction (PCR).
Gene_expression (expression) of interleukin-1 in brains associated with necrosis, cancer and adhesions
2) Confidence 0.04 Published 1997 Journal J. Neurovirol. Section Abstract Doc Link 9475112 Disease Relevance 2.34 Pain Relevance 0.15

General Comments

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