INT73731

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Context Info
Confidence 0.33
First Reported 1998
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 14.58
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (RAPH1) plasma membrane (RAPH1) cytoskeleton (RAPH1)
cytoplasm (RAPH1)
Anatomy Link Frequency
T cell 1
RAPH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
endometriosis 4 97.96 Very High Very High Very High
pain pelvic 12 90.24 High High
agonist 5 85.68 High High
rheumatoid arthritis 4 75.28 Quite High
peripheral neuropathy 2 71.96 Quite High
abdominal pain 9 59.44 Quite High
Pain 7 12.32 Low Low
Spinal cord 10 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Action potential 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lymphoproliferative Disease 95 100.00 Very High Very High Very High
Motor Neuron Diseases 88 100.00 Very High Very High Very High
Infection 118 99.98 Very High Very High Very High
Epstein-barr Virus 250 99.78 Very High Very High Very High
Syndrome 72 99.36 Very High Very High Very High
Leukemia 30 99.18 Very High Very High Very High
Organ Transplantation 3 99.08 Very High Very High Very High
Pruritus 6 98.84 Very High Very High Very High
Disease 54 98.72 Very High Very High Very High
T-cell Lymphoma 60 98.56 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A MEDLINE search of the English language literature revealed no report of associations between multiple malformations and LPD.
LPD Neg (no) Binding (associations) of
1) Confidence 0.33 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1481579 Disease Relevance 1.39 Pain Relevance 0.12
Lymphoproliferative disorder (LPD) is a well recognized complication of solid organ transplantation.
LPD Binding (recognized) of associated with organ transplantation and lymphoproliferative disease
2) Confidence 0.30 Published 1998 Journal J. Formos. Med. Assoc. Section Abstract Doc Link 9481067 Disease Relevance 1.12 Pain Relevance 0.06
On the basis of these observations, we can affirm that no established guidelines exist regarding the management of LPD.
LPD Binding (management) of
3) Confidence 0.25 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1481579 Disease Relevance 0.93 Pain Relevance 0.10
LPD can be associated with other oestrogen-dependent diseases including endometriosis, ovarian clear cell carcinoma, endometrial carcinoma [17] and ovarian fibrothecoma [2].
LPD Binding (associated) of associated with endometriosis, carcinoma, endometrial cancer and disease
4) Confidence 0.24 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1481579 Disease Relevance 0.63 Pain Relevance 0.05
No reports of multiple congenital malformations associated with LPD have been found in the English literature.


LPD Binding (associated) of
5) Confidence 0.24 Published 2006 Journal BMC Cancer Section Abstract Doc Link PMC1481579 Disease Relevance 0.91 Pain Relevance 0.09
Furthermore we describe the association of LPD with Raynaud's syndrome and Prurigo nodularis.


LPD Binding (association) of associated with syndrome and pruritus
6) Confidence 0.22 Published 2005 Journal BMC Gastroenterol Section Abstract Doc Link PMC1266363 Disease Relevance 0.92 Pain Relevance 0
The association between MND and LPD could be coincidental, but LPD seems to be disproportionately frequent in patients with MND compared to the population in general [5].
LPD Binding (association) of associated with lymphoproliferative disease and motor neuron diseases
7) Confidence 0.04 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2941760 Disease Relevance 1.68 Pain Relevance 0.04
The clinicopathology of patients with acute HLH, chronic active EBV infection associated with NK or T LPD, and B-LPD of various spectra arising in the background of chronic EBV infection was summarized in Table 2-4.
LPD Binding (associated) of associated with epstein-barr virus, lymphoproliferative disease and infection
8) Confidence 0.02 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526432 Disease Relevance 3.87 Pain Relevance 0.04
Median patient survivals for each category of T or NK EBV-positive LPDs were 2 months for acute HLH, 1.6 months for ANKL, 5.5 months for PTCL, 8 months for T/NK LPD associated with CAEBV, and 13.2 months for NK/T cell lymphomas.
LPD Binding (associated) of in T cell associated with t-cell lymphoma, leukemia, epstein-barr virus and lymphoproliferative disease
9) Confidence 0.02 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526432 Disease Relevance 3.15 Pain Relevance 0

General Comments

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