INT73743

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Context Info
Confidence 0.24
First Reported 1998
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 6.27
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (TECR) endoplasmic reticulum (TECR) cytoplasm (TECR)
Anatomy Link Frequency
plasma 3
podocytes 1
HCT-8 1
TECR (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory mediators 12 56.16 Quite High
Inflammation 36 55.32 Quite High
cytokine 20 47.84 Quite Low
qutenza 1 42.32 Quite Low
Pain 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Carcinoma 1 99.66 Very High Very High Very High
Acute Renal Failure 332 98.90 Very High Very High Very High
Burns 296 98.68 Very High Very High Very High
Proteinuria 132 85.72 High High
Glycosuria 4 81.52 Quite High
Apoptosis 164 78.80 Quite High
Congenital Anomalies 4 76.60 Quite High
Injury 60 70.32 Quite High
INFLAMMATION 52 56.16 Quite High
Renal Disease 20 53.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using HCT-8 cells, a cell line from a human ileocoecal carcinoma, we studied the effects of spices on transepithelial electrical resistance (TER), permeability for fluorescein isothiocyanate (FITC)-labeled dextrans with graded molecular weight, and morphological alterations of tight junctions by immunofluorescence using an anti-ZO-1 antibody, a marker for tight junction integrity.
Regulation (effects) of TER in HCT-8 associated with carcinoma
1) Confidence 0.24 Published 1998 Journal J. Nutr. Section Abstract Doc Link 9482766 Disease Relevance 0.10 Pain Relevance 0
After challenge of tubular cells with burns septic ARF group plasma, we observed a marked decrease of ZO-1 expression with a simultaneous alteration of TER.
Regulation (alteration) of TER in plasma associated with acute renal failure and burns
2) Confidence 0.09 Published 2008 Journal Crit Care Section Body Doc Link PMC2447585 Disease Relevance 1.05 Pain Relevance 0.03
After incubation with burns septic ARF group plasma, tubular cells exhibited significantly lower TER values in comparison to healthy controls (Figure 5F).
Regulation (values) of TER in plasma associated with acute renal failure and burns
3) Confidence 0.08 Published 2008 Journal Crit Care Section Body Doc Link PMC2447585 Disease Relevance 1.93 Pain Relevance 0.03
After incubation with burns septic ARF group plasma, podocytes exhibited significantly lower TER values in comparison with healthy controls (Figure 6A).
Regulation (values) of TER in podocytes associated with acute renal failure and burns
4) Confidence 0.08 Published 2008 Journal Crit Care Section Body Doc Link PMC2447585 Disease Relevance 1.59 Pain Relevance 0
After incubation with burns septic ARF group plasma, podocytes exhibited significantly lower TER values in comparison with healthy controls (Figure 6A).
Regulation (values) of TER in plasma associated with acute renal failure and burns
5) Confidence 0.03 Published 2008 Journal Crit Care Section Body Doc Link PMC2447585 Disease Relevance 1.59 Pain Relevance 0

General Comments

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