INT73750

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Context Info
Confidence 0.44
First Reported 1998
Last Reported 2006
Negated 2
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 0.28
Pain Relevance 3.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (YY1) chromosome organization (YY1) RNA binding (YY1)
plasma membrane (YY1) nucleus (YY1) intracellular (YY1)
Anatomy Link Frequency
spinal cord 3
naive T cells 2
dorsal root ganglia 1
YY1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Delta opioid receptors 36 100.00 Very High Very High Very High
gABA 16 100.00 Very High Very High Very High
opioid receptor 5 100.00 Very High Very High Very High
Spinal cord 12 99.16 Very High Very High Very High
alcohol 2 96.88 Very High Very High Very High
Potency 1 95.88 Very High Very High Very High
analgesia 2 93.60 High High
tetrodotoxin 2 93.56 High High
agonist 12 92.96 High High
Enkephalin 2 85.16 High High
Disease Link Frequency Relevance Heat
Hyperplasia 1 87.92 High High
Alcohol Addiction 2 83.00 Quite High
Ganglion Cysts 4 52.44 Quite High
Nociception 2 35.40 Quite Low
Bordatella Infection 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Phylogenetic changes in the expression of delta opioid receptors in spinal cord and dorsal root ganglia.
Regulation (changes) of Gene_expression (expression) of delta in spinal cord associated with delta opioid receptors and spinal cord
1) Confidence 0.44 Published 2003 Journal J. Comp. Neurol. Section Title Doc Link 12966560 Disease Relevance 0.05 Pain Relevance 0.70
We identified that, in the splenocytes, delta opioid receptor expression is tightly controlled by negative feedback regulation of micro opioid receptors.
Regulation (controlled) of Gene_expression (expression) of delta associated with opioid receptor
2) Confidence 0.44 Published 2004 Journal J. Immunol. Section Abstract Doc Link 15210757 Disease Relevance 0.08 Pain Relevance 0.75
The pharmacological and clinical activities of THIP probably reflect its potent effects at extrasynaptic GABA(A) receptors insensitive to benzodiazepines and containing alpha(4)beta(3)delta subunits.
Regulation (effects) of Gene_expression (containing) of delta associated with gaba
3) Confidence 0.44 Published 2004 Journal Biochem. Pharmacol. Section Abstract Doc Link 15451401 Disease Relevance 0 Pain Relevance 1.12
Expression in other layers and expression of CaMKII-gamma and delta were unaffected.
Neg (unaffected) Regulation (unaffected) of Gene_expression (expression) of delta
4) Confidence 0.26 Published 1998 Journal J. Neurosci. Section Abstract Doc Link 9482799 Disease Relevance 0 Pain Relevance 0.16
Expression in other layers and expression of CaMKII-gamma and delta were unaffected.
Neg (unaffected) Regulation (unaffected) of Gene_expression (Expression) of delta
5) Confidence 0.26 Published 1998 Journal J. Neurosci. Section Abstract Doc Link 9482799 Disease Relevance 0 Pain Relevance 0.16
Activation of naive T cells markedly up-regulates the expression of delta opioid receptors (DORs).
Regulation (regulates) of Gene_expression (expression) of delta in naive T cells associated with delta opioid receptors
6) Confidence 0.26 Published 2006 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 16249373 Disease Relevance 0.09 Pain Relevance 0.32
Phylogenetic changes in the expression of delta opioid receptors in spinal cord and dorsal root ganglia.
Regulation (changes) of in dorsal root ganglia Gene_expression (expression) of delta in spinal cord associated with delta opioid receptors and spinal cord
7) Confidence 0.15 Published 2003 Journal J. Comp. Neurol. Section Title Doc Link 12966560 Disease Relevance 0.05 Pain Relevance 0.70

General Comments

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