INT73755

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Context Info
Confidence 0.81
First Reported 1998
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.82
Pain Relevance 1.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Scn10a) transmembrane transport (Scn10a)
Anatomy Link Frequency
neuronal 1
epidermis 1
Scn10a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
sodium channel 9 98.36 Very High Very High Very High
Sciatic nerve 3 96.76 Very High Very High Very High
dorsal root ganglion 5 95.20 Very High Very High Very High
Eae 4 91.00 High High
Neuropathic pain 5 89.76 High High
Peripheral nerve injury 1 88.16 High High
Lasting pain 1 85.88 High High
Spinal cord 1 83.32 Quite High
hyperexcitability 1 81.44 Quite High
Pain 6 76.48 Quite High
Disease Link Frequency Relevance Heat
Injury 6 97.88 Very High Very High Very High
Ganglion Cysts 5 95.20 Very High Very High Very High
Neuropathic Pain 6 89.76 High High
Pain 4 85.88 High High
Nociception 2 84.04 Quite High
Complex Regional Pain Syndromes 3 68.40 Quite High
Herpes Simplex Virus Infection 1 64.72 Quite High
Neuralgia 3 64.00 Quite High
Nervous System Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The alteration in immunolabeling was attributed to translocation of presynthesized, intracellularly located PN3 protein from neuronal somata to peripheral axons, with subsequent accumulation at the site of injury.
Localization (translocation) of PN3 protein in neuronal associated with injury
1) Confidence 0.81 Published 1998 Journal J. Neurosci. Section Abstract Doc Link 9482802 Disease Relevance 0.89 Pain Relevance 0.87
Na(v)1.1, Na(v)1.6, and Na(v)1.8 were localized within keratinocytes in rat epidermis.
Localization (localized) of Na(v)1.8 in epidermis
2) Confidence 0.68 Published 2008 Journal Pain Section Abstract Doc Link 18442883 Disease Relevance 0.92 Pain Relevance 0.89

General Comments

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