INT73854

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Context Info
Confidence 0.52
First Reported 1998
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.26
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ABL1) protein modification process (ABL1) mitochondrion (ABL1)
nucleolus (ABL1) nucleus (ABL1) DNA binding (ABL1)
Anatomy Link Frequency
knee joint 1
ABL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 3 95.76 Very High Very High Very High
dexamethasone 2 94.48 High High
Pain 3 92.84 High High
methotrexate 1 91.60 High High
vincristine 1 74.48 Quite High
Central nervous system 1 65.84 Quite High
iatrogenic 3 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
IPN 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 1 93.36 High High
Pain 2 92.84 High High
Leukemia 11 91.56 High High
Cancer 16 85.32 High High
Hematological Disease 1 84.88 Quite High
Hepatitis C Virus Infection 22 84.72 Quite High
Recurrence 4 82.88 Quite High
Familial Dysautonomia 121 77.56 Quite High
Hepatitis B Virus Infection 37 74.20 Quite High
Hepatitis 9 73.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fluid from the knee joint included leukemic cells consistent with the immunophenotype of blasts prior to BMT and also revealed the bcr/abl transcript by reverse-transcriptase polymerase chain reaction.
Transcription (transcript) of bcr/abl in knee joint
1) Confidence 0.52 Published 1998 Journal Bone Marrow Transplant. Section Abstract Doc Link 9489661 Disease Relevance 0.44 Pain Relevance 0.14
The number of IKBKAP and ABL1 transcripts was extrapolated automatically by the Sequence Detection System v2.2.2 software (Applied Biosystems).


Transcription (transcripts) of ABL1
2) Confidence 0.43 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3004942 Disease Relevance 0.08 Pain Relevance 0
This PCR allows (i) to demonstrate the sensitivity of the RT-PCR, because ABL is only moderately transcribed in human cells, and (ii) to distinguish between the cDNA and residual genomic DNA, because the primers are located in two different exons of the ABL gene.
Transcription (transcribed) of ABL
3) Confidence 0.39 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2861168 Disease Relevance 1.13 Pain Relevance 0
PCR-analysis revealed no evidence of BCR-ABL fusion transcripts.
Transcription (transcripts) of BCR-ABL
4) Confidence 0.19 Published 2010 Journal Diagn Pathol Section Body Doc Link PMC2853499 Disease Relevance 0.61 Pain Relevance 0.20

General Comments

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