INT73855

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Context Info
Confidence 0.02
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Jun) extracellular region (Pdyn) aging (Jun)
plasma membrane (Pdyn) nucleus (Jun) DNA binding (Jun)
Anatomy Link Frequency
neurons 2
Jun (Rattus norvegicus)
Pdyn (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 1 99.28 Very High Very High Very High
Pain 1 25.00 Low Low
Enkephalin 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Prodynorphin cyclic AMP-responsive element 2 (DynCRE2), DynCRE3, and the noncanonical prodynorphin AP-1 (ncDynAP-1) regulatory sites control, in a coordinated manner, prodynorphin induction in the spinal cord after noxious stimulation, whereas prodynorphin up-regulation in supraoptic neurons is regulated predominantly by the ncDynAP-1.
ncDynAP-1 Regulation (regulated) of Regulation (regulation) of prodynorphin in neurons associated with spinal cord
1) Confidence 0.02 Published 1998 Journal J. Neurochem. Section Abstract Doc Link 9489710 Disease Relevance 0 Pain Relevance 0.05

General Comments

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