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Context Info
Confidence 0.19
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (CCNT1) small molecule metabolic process (CYP2B6) endoplasmic reticulum (CYP2B6)
nucleolus (CCNT1) nucleus (CCNT1) cell cycle (CCNT1)
Anatomy Link Frequency
liver 1
CCNT1 (Homo sapiens)
CYP2B6 (Homo sapiens)
Pain Link Frequency Relevance Heat
methadone 7 83.20 Quite High
Buprenorphine 7 82.08 Quite High
Potency 1 33.44 Quite Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 3 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ritonavir, indinavir, and saquinavir, all human immunodeficiency virus-1 protease inhibitors with a potent antiviral effect during triple therapy, are extensively metabolized by liver cytochrome P450 3A4.
immunodeficiency virus-1 protease Binding (metabolized) of P450 in liver associated with acquired immune deficiency syndrome or hiv infection
1) Confidence 0.19 Published 1998 Journal Drug Metab. Dispos. Section Abstract Doc Link 9492389 Disease Relevance 0.17 Pain Relevance 0.56

General Comments

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