INT73925

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Context Info
Confidence 0.22
First Reported 1998
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.19
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

methyltransferase activity (FBL) nucleolus (FBL) RNA binding (FBL)
nucleus (FBL)
Anatomy Link Frequency
FIB 1
FBL (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 1 98.94 Very High Very High Very High
cINOD 1 98.26 Very High Very High Very High
rheumatoid arthritis 54 79.68 Quite High
fibrosis 63 64.24 Quite High
Arthritis 7 37.28 Quite Low
Osteoarthritis 3 36.44 Quite Low
corticosteroid 2 5.00 Very Low Very Low Very Low
methotrexate 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Leflunomide 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 3 99.38 Very High Very High Very High
INFLAMMATION 2 98.14 Very High Very High Very High
Toxicity 1 97.20 Very High Very High Very High
Coagulation Disorder 1 94.60 High High
Hepatotoxicity 3 94.04 High High
Hepatitis C Virus Infection 34 87.72 High High
Diabetes Mellitus 2 80.00 Quite High
Rheumatoid Arthritis 54 79.68 Quite High
Cardiovascular Disease 1 79.20 Quite High
Metabolic Syndrome 1 78.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Prostaglandin E1 inhibited collagen production in both types of FIB, but nonsteroidal anti-inflammatory drugs and interleukin-1beta, a cytokine involved in the wound-healing process, had opposite effects on gastric and skin FIB.
Regulation (effects) of FIB in FIB associated with inflammation, injury, cinod and cytokine
1) Confidence 0.22 Published 1998 Journal Eur Surg Res Section Abstract Doc Link 9493694 Disease Relevance 0.34 Pain Relevance 0.15
However, the simple indexes (APRI, FIB-4, HGM-1 and HGM-2) are calculated in a relatively easy way using parameters easily available in routine clinical practice.
Regulation (calculated) of FIB-4
2) Confidence 0.04 Published 2010 Journal BMC Infect Dis Section Body Doc Link PMC2936897 Disease Relevance 1.64 Pain Relevance 0.06
There were some non-significant differences in sensitivities of the AhFibA and anti-CCP2 assay between populations 1 and 2.
Regulation (sensitivities) of AhFibA
3) Confidence 0.02 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779401 Disease Relevance 0.21 Pain Relevance 0.10

General Comments

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