INT73939

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Context Info
Confidence 0.57
First Reported 1997
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 6.30
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Cd36) transport (Cd36) mitochondrion (Cd36)
cell adhesion (Cd36) Golgi apparatus (Cd36) plasma membrane (Cd36)
Anatomy Link Frequency
platelets 1
ampulla 1
reticulocytes 1
heart 1
Cd36 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Angina 11 94.08 High High
Inflammation 24 83.04 Quite High
Pain 2 69.40 Quite High
agonist 43 50.00 Quite Low
ischemia 4 5.00 Very Low Very Low Very Low
dexamethasone 3 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Heart Disease 18 99.74 Very High Very High Very High
Heart Disease 12 97.60 Very High Very High Very High
Pathologic Processes 1 94.80 High High
Angina 3 94.08 High High
Cancer 147 91.96 High High
Dyspnea 3 91.84 High High
Apoptosis 27 91.28 High High
Acute Coronary Syndrome 3 87.32 High High
Sickle Cell Anemia 6 87.20 High High
Adhesions 10 86.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
[Different patterns of 123I-BMIPP myocardial accumulation in patients with type I and II CD36 deficiency].
Negative_regulation (deficiency) of CD36
1) Confidence 0.57 Published 1997 Journal Kaku Igaku Section Title Doc Link 9494334 Disease Relevance 1.49 Pain Relevance 0.29
CD36 deficiency was observed in a higher proportion (12%) of patients with heart disease in this study than in a reported control study.
Negative_regulation (deficiency) of CD36 in heart associated with heart disease
2) Confidence 0.42 Published 1997 Journal Kaku Igaku Section Abstract Doc Link 9494334 Disease Relevance 1.56 Pain Relevance 0.30
The angiogenic EC phenotype is characterized by marked downregulation of CD36/fatty acid translocase (FAT) [222].
Negative_regulation (downregulation) of fatty acid translocase
3) Confidence 0.42 Published 2010 Journal PPAR Research Section Body Doc Link PMC2829627 Disease Relevance 1.04 Pain Relevance 0.04
Takotsubo-shaped cardiomyopathy with type I CD36 deficiency.
Negative_regulation (deficiency) of CD36 associated with coronary heart disease
4) Confidence 0.42 Published 2005 Journal Heart Vessels Section Title Doc Link 15912310 Disease Relevance 0.55 Pain Relevance 0.09
A transient left ventricular apical ballooning (so-called "ampulla" or "Takotsubo-shaped" cardiomyopathy) with type I CD36 deficiency is described in a 71-year-old woman.
Negative_regulation (deficiency) of CD36 in ampulla associated with coronary heart disease
5) Confidence 0.42 Published 2005 Journal Heart Vessels Section Abstract Doc Link 15912310 Disease Relevance 0.52 Pain Relevance 0.09
No CD36 expression in either platelets or monocytes/macrophages was shown using flow cytometer analysis and type I CD36 deficiency was diagnosed.
Negative_regulation (deficiency) of CD36 in platelets
6) Confidence 0.42 Published 2005 Journal Heart Vessels Section Abstract Doc Link 15912310 Disease Relevance 0.69 Pain Relevance 0.06
Flow cytometry showed that CD36 was absent from the circulating red blood cells and reticulocytes of platelet CD36--deficient individuals but present on those from patients with normal platelet CD36 expression, and that alpha(4)beta(1) integrin levels were similar on the reticulocytes of the 2 groups.
Negative_regulation (absent) of CD36 in reticulocytes
7) Confidence 0.40 Published 2001 Journal Blood Section Abstract Doc Link 11493440 Disease Relevance 0.45 Pain Relevance 0.07

General Comments

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