INT74017

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.43
First Reported 1998
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 6
Disease Relevance 7.59
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (VHL) mitochondrion (VHL) cell morphogenesis (VHL)
endoplasmic reticulum (VHL) nucleus (VHL) extracellular matrix organization (VHL)
Anatomy Link Frequency
germline 1
VHL (Homo sapiens)
Pain Link Frequency Relevance Heat
Analgesic 1 92.80 High High
medulla 2 63.84 Quite High
Catecholamine 2 63.52 Quite High
Spinal cord 2 14.20 Low Low
imagery 17 13.04 Low Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
noradrenaline 2 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 259 100.00 Very High Very High Very High
Cancer 143 99.96 Very High Very High Very High
Disease 200 99.52 Very High Very High Very High
Renal Cancer 115 99.14 Very High Very High Very High
Nicotine Addiction 1 92.28 High High
Tuberous Sclerosis 1 89.16 High High
Pheochromocytoma 92 88.92 High High
Renal Disease 1 85.08 High High
Hypoxia 16 77.72 Quite High
Polycystic Kidney Disease 4 76.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IHMBR operated on this patient and is involved in fundamental studies on VHL
Regulation (involved) of VHL associated with syndrome
1) Confidence 0.43 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC2169240 Disease Relevance 0.86 Pain Relevance 0.03
inheriting the mutant VHL gene; but the degree of clinical severity is
Regulation (degree) of VHL
2) Confidence 0.39 Published 2008 Journal Advances in Urology Section Body Doc Link PMC2581790 Disease Relevance 0.65 Pain Relevance 0
Over 300 different VHL germline mutations have been
Regulation (different) of VHL in germline
3) Confidence 0.39 Published 2008 Journal Advances in Urology Section Body Doc Link PMC2581790 Disease Relevance 0.32 Pain Relevance 0
A group of VHL mutations termed type 1, comprising mostly deletions and
Regulation (group) of VHL
4) Confidence 0.39 Published 2008 Journal Advances in Urology Section Body Doc Link PMC2581790 Disease Relevance 0.63 Pain Relevance 0
Solid RCC of the clear cell type is associated with alterations in the VHL tumor suppressor gene and hereditary papillary RCC is associated with alterations of the c-met protooncogene.
Regulation (alterations) of VHL associated with cancer, syndrome and renal cancer
5) Confidence 0.26 Published 1998 Journal Toxicol Pathol Section Abstract Doc Link 9502393 Disease Relevance 1.90 Pain Relevance 0.09
It is presumed that the genotype-phenotype correlation in VHL disease is a reflection of the altered pVHL function caused by a mutation.
Regulation (altered) of pVHL associated with syndrome and disease
6) Confidence 0.26 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC2169240 Disease Relevance 3.23 Pain Relevance 0.03

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox