INT74032

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Context Info
Confidence 0.48
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.11
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Jun) extracellular space (Igf1) aging (Jun)
extracellular region (Igf1) nucleus (Jun) DNA binding (Jun)
Igf1 (Rattus norvegicus)
Jun (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 2 25.00 Low Low
Neuropeptide 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Pheochromocytoma 2 55.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, AP1 by itself is not sufficient to increase PENK transcription, as insulin-like growth factor 1 (IGF1), which stimulates AP1 activity but not cAMP production, is unable to stimulate PENK transcription.
IGF1 Positive_regulation (stimulates) of AP1
1) Confidence 0.48 Published 1998 Journal DNA Cell Biol. Section Abstract Doc Link 9502431 Disease Relevance 0.05 Pain Relevance 0
However, AP1 by itself is not sufficient to increase PENK transcription, as insulin-like growth factor 1 (IGF1), which stimulates AP1 activity but not cAMP production, is unable to stimulate PENK transcription.
insulin-like growth factor 1 Positive_regulation (stimulates) of AP1
2) Confidence 0.48 Published 1998 Journal DNA Cell Biol. Section Abstract Doc Link 9502431 Disease Relevance 0.06 Pain Relevance 0

General Comments

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