INT74101

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Context Info
Confidence 0.06
First Reported 1998
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.20
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Adm) aging (Adm) extracellular region (Adm)
response to stress (Adm) cytoplasm (Adm)
Anatomy Link Frequency
plasma 1
horn 1
Adm (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dorsal horn 2 99.68 Very High Very High Very High
Spinal cord 2 99.16 Very High Very High Very High
tetrodotoxin 3 93.52 High High
Sciatic nerve 1 75.00 Quite High
Dorsal horn neuron 1 72.88 Quite High
Pain 12 28.84 Quite Low
antagonist 10 6.36 Low Low
Serotonin 8 5.36 Low Low
Calcium channel 10 5.00 Very Low Very Low Very Low
ischemia 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 80 100.00 Very High Very High Very High
Systemic Sclerosis 29 96.46 Very High Very High Very High
Ulcers 39 83.12 Quite High
Injury 4 61.72 Quite High
Apoptosis 18 43.84 Quite Low
Pain 9 28.84 Quite Low
Hypesthesia 4 16.68 Low Low
Stress 20 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 16 5.00 Very Low Very Low Very Low
Sprains And Strains 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Following axotomy, AP and NDP were decreased in the dorsal horn and increased in large cells in the dorsolateral motor nuclei while CO was decreased in ventral horn neuropil.
Negative_regulation (decreased) of AP in horn associated with dorsal horn
1) Confidence 0.06 Published 1998 Journal Neuroreport Section Abstract Doc Link 9507983 Disease Relevance 0 Pain Relevance 0.53
In AP partial disruption of occludin was seen in crypts as well as in villi.
Negative_regulation (disruption) of AP associated with pancreatitis
2) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2639703 Disease Relevance 0.76 Pain Relevance 0
In a cold challenge test assessed by photoelectric plethysmography, mean recovery time fell by approximately 70%.94 In a subsequent assessment of the long-term use of N-acetylcysteine in patients with RP secondary to systemic sclerosis, patients treated with an intravenous dose of 15 mg/kg/hour for 5 consecutive hours every 2 weeks from October to May for 2 years demonstrated increased global hand perfusion, reduced plasma adrenomedullin levels, and reduced frequency and severity of RP attacks.
Negative_regulation (reduced) of adrenomedullin in plasma associated with systemic sclerosis
3) Confidence 0.03 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2860448 Disease Relevance 0.44 Pain Relevance 0

General Comments

This test has worked.

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