INT74159

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Context Info
Confidence 0.60
First Reported 1998
Last Reported 2005
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 4
Disease Relevance 1.66
Pain Relevance 3.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ngf, Calca) aging (Ngf, Calca) extracellular region (Ngf, Calca)
signal transduction (Ngf) nucleus (Calca) intracellular (Calca)
Anatomy Link Frequency
nerve 4
primary sensory neurons 2
nociceptor 2
Ngf (Rattus norvegicus)
Calca (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 36 100.00 Very High Very High Very High
Nerve growth factor 31 100.00 Very High Very High Very High
calcitonin gene related peptide 7 100.00 Very High Very High Very High
nociceptor 1 100.00 Very High Very High Very High
Peripheral nerve injury 3 99.04 Very High Very High Very High
Neuropathic pain 12 95.48 Very High Very High Very High
dorsal root ganglion 2 75.00 Quite High
Dorsal horn 6 64.56 Quite High
Disease Link Frequency Relevance Heat
Nervous System Injury 9 99.28 Very High Very High Very High
Injury 3 96.00 Very High Very High Very High
Neuropathic Pain 12 95.48 Very High Very High Very High
Ganglion Cysts 2 75.00 Quite High
Increased Venous Pressure Under Development 1 62.48 Quite High
Nociception 1 56.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results indicate independent regulation of CGRP expression and nociceptor physiology by NGF.
NGF Neg (independent) Regulation (regulation) of Gene_expression (expression) of CGRP in nociceptor associated with calcitonin gene related peptide and nociceptor
1) Confidence 0.60 Published 1998 Journal J. Comp. Neurol. Section Abstract Doc Link 9514512 Disease Relevance 0.27 Pain Relevance 0.48
In adult animals, the expression of CGRP is regulated by nerve growth factor (NGF).
NGF Regulation (regulated) of Gene_expression (expression) of CGRP in nerve associated with nerve growth factor and calcitonin gene-related peptide
2) Confidence 0.44 Published 2005 Journal Brain Res. Section Abstract Doc Link 15823252 Disease Relevance 0.48 Pain Relevance 0.87
In adult animals, the expression of CGRP is regulated by nerve growth factor (NGF).
nerve growth factor Regulation (regulated) of Gene_expression (expression) of CGRP in nerve associated with nerve growth factor and calcitonin gene-related peptide
3) Confidence 0.44 Published 2005 Journal Brain Res. Section Abstract Doc Link 15823252 Disease Relevance 0.48 Pain Relevance 0.86
The effect of endoneurial nerve growth factor on calcitonin gene-related peptide expression in primary sensory neurons.
nerve growth factor Regulation (effect) of Gene_expression (expression) of calcitonin in primary sensory neurons associated with nerve growth factor and calcitonin gene-related peptide
4) Confidence 0.19 Published 2005 Journal Brain Res. Section Title Doc Link 15823252 Disease Relevance 0.44 Pain Relevance 1.01

General Comments

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