INT74292

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Context Info
Confidence 0.37
First Reported 1998
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.30
Pain Relevance 2.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (GLRA1) intracellular (GLRA1) transmembrane transport (GLRA1)
Anatomy Link Frequency
spinal 1
gray matter 1
GLRA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 91 100.00 Very High Very High Very High
Glutamate 7 99.46 Very High Very High Very High
Neuropathic pain 11 98.08 Very High Very High Very High
Neurotransmitter 3 96.36 Very High Very High Very High
Spinal cord 7 95.16 Very High Very High Very High
Hyperalgesia 10 92.96 High High
cINOD 9 92.88 High High
Inflammation 32 92.44 High High
Paracetamol 1 92.24 High High
diclofenac 1 91.04 High High
Disease Link Frequency Relevance Heat
Neuropathic Pain 24 98.08 Very High Very High Very High
Hyperalgesia 11 92.96 High High
INFLAMMATION 40 92.44 High High
Nervous System Injury 13 87.24 High High
Pain 121 86.20 High High
Injury 11 74.72 Quite High
Inflammatory Pain 7 51.52 Quite High
Frailty 48 50.00 Quite Low
Arthritis 4 50.00 Quite Low
Nociception 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Glycine receptor reduction within segmental gray matter in a rat model in neuropathic pain.
Negative_regulation (reduction) of Glycine receptor in gray matter associated with pain and neuropathic pain
1) Confidence 0.37 Published 1998 Journal Neurol. Res. Section Title Doc Link 9522353 Disease Relevance 0.64 Pain Relevance 0.98
Several mechanisms have been proposed, including EP1 receptor activation and spinal release of glutamate as well as loss of spinal glycine receptor mediated inhibition [59].
Negative_regulation (inhibition) of glycine receptor in spinal associated with glutamate
2) Confidence 0.00 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2206352 Disease Relevance 0.66 Pain Relevance 1.36

General Comments

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