INT74297

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Context Info
Confidence 0.75
First Reported 1998
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.40
Pain Relevance 1.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Nt5e) cytoplasm (Nt5e)
Anatomy Link Frequency
neuronal 1
Nt5e (Rattus norvegicus)
Pain Link Frequency Relevance Heat
c fibre 1 99.66 Very High Very High Very High
Morphine 3 95.60 Very High Very High Very High
cerebral cortex 4 93.52 High High
Spinal cord 4 92.72 High High
adenocard 3 89.08 High High
antagonist 2 85.52 High High
antinociception 1 80.04 Quite High
Opioid 2 79.40 Quite High
Pain 3 56.72 Quite High
Inflammation 15 50.00 Quite Low
Disease Link Frequency Relevance Heat
Nociception 4 97.04 Very High Very High Very High
Nervous System Malformation 1 77.04 Quite High
Liver Cancer 11 63.96 Quite High
Hepatocellular Cancer 76 50.00 Quite Low
Hepatitis C Virus Infection 72 50.00 Quite Low
INFLAMMATION 17 50.00 Quite Low
Ganglion Cysts 1 34.56 Quite Low
Cancer 17 23.76 Low Low
Apoptosis 5 20.68 Low Low
Cirrhosis 28 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Gallic acid treatment significantly attenuated some alterations (i.e. increased levels of aspartate transaminase, alanine transaminase, alkaline phosphatase, acid phosphatase, lactate dehydrogenase, gamma-glutamyltransferase, 5'-nucleotidase, bilirubin, alpha-fetoprotein, carcinoembryonic antigen) and decreased the levels of argyophillic nucleolar organizing regions (AgNORs) and proliferating cell nuclear antigen (PCNA) [90].
Gene_expression (levels) of 5'-nucleotidase
1) Confidence 0.75 Published 2010 Journal J Transl Med Section Body Doc Link PMC2991329 Disease Relevance 0.06 Pain Relevance 0
Additionally, we evaluated E-NTPDase (1, 2 and 3) and ecto-5'nucleotidase gene expression by semi-quantitative RT-PCR analysis.
Gene_expression (expression) of nucleotidase
2) Confidence 0.50 Published 2010 Journal Eur. J. Pharmacol. Section Abstract Doc Link 20553911 Disease Relevance 0.16 Pain Relevance 0.96
Trigeminal stimulation of C-fibers increased c-fos expression within the trigeminal nucleus caudalis (NtV) and thalamic neuronal activity which both reflect the transmission of a nociceptive message.
Gene_expression (expression) of NtV in neuronal associated with nociception and c fibre
3) Confidence 0.05 Published 1998 Journal Fundam Clin Pharmacol Section Abstract Doc Link 9523190 Disease Relevance 0.17 Pain Relevance 0.18

General Comments

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