INT74395

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Context Info
Confidence 0.03
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Htr2b, Pdyn) extracellular region (Pdyn) cytoplasm (Htr2b)
signal transducer activity (Htr2b)
Htr2b (Rattus norvegicus)
Pdyn (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 1 98.60 Very High Very High Very High
fluoxetine 6 85.04 High High
gABA 1 77.12 Quite High
Enkephalin 1 76.76 Quite High
Neuropeptide 3 75.00 Quite High
Nucleus accumbens 2 69.32 Quite High
agonist 1 47.84 Quite Low
Serotonin 2 47.28 Quite Low
Disease Link Frequency Relevance Heat
Generalized Anxiety Disorder 1 40.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This observation, together with our previous finding that the 5-HT2 antagonist ritanserin tends to increase preprodynorphin mRNA levels, suggests a 5-HT2-mediated tonic inhibition of preprodynorphin mRNA levels.
5-HT2 Negative_regulation (inhibition) of preprodynorphin mRNA associated with antagonist
1) Confidence 0.03 Published 1998 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 9526047 Disease Relevance 0 Pain Relevance 0.61

General Comments

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