INT74424

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Context Info
Confidence 0.31
First Reported 1998
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.91
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL10) extracellular region (IL10) intracellular (IL10)
cell-cell signaling (IL10) response to stress (IL10)
IL10 (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 4 99.74 Very High Very High Very High
cytokine 144 97.00 Very High Very High Very High
antagonist 34 93.40 High High
Inflammation 125 83.08 Quite High
Inflammatory response 10 77.76 Quite High
chemokine 23 45.32 Quite Low
agonist 20 5.00 Very Low Very Low Very Low
methotrexate 4 5.00 Very Low Very Low Very Low
Inflammatory stimuli 4 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 315 93.92 High High
INFLAMMATION 141 83.08 Quite High
Necrosis 4 79.96 Quite High
Cancer 6 79.60 Quite High
Eosinophilia 19 68.20 Quite High
Occupational Lung Diseases 15 31.84 Quite Low
Hypersensitivity 9 7.36 Low Low
Targeted Disruption 21 5.00 Very Low Very Low Very Low
Infection 19 5.00 Very Low Very Low Very Low
Disease 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The aim of the present study was to investigate if choice of anaesthesia, based on high-dose opioids (fentanyl) versus low-dose opioids influenced the release of IL-6, IL-8, and IL-10.
Regulation (influenced) of Localization (release) of IL-10 associated with opioid
1) Confidence 0.31 Published 1998 Journal Acta Anaesthesiol Scand Section Abstract Doc Link 9527747 Disease Relevance 0.32 Pain Relevance 0.65
Treatment with LPS had no statistically significant effect on IL-10 release from the amniotic side of the membranes but stimulated release from the choriodecidual side (Fig. 2C; ANOVA side specificity effect, p < 0.001; ANOVA treatment effect, p = 0.036; ANOVA treatment * membrane side interaction, p = 0.005).
Neg (no) Regulation (effect) of Localization (release) of IL-10
2) Confidence 0.25 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2774314 Disease Relevance 0 Pain Relevance 0
 ; molecules related to IL-10 (IL-19, IL-20, IL-22, IL-24, IL-26); and the IFN-?
Regulation (molecules) of Localization (related) of IL-10
3) Confidence 0.08 Published 2008 Journal J Occup Med Toxicol Section Body Doc Link PMC2259400 Disease Relevance 0.59 Pain Relevance 0.28

General Comments

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