INT745

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Context Info
Confidence 0.78
First Reported 1979
Last Reported 2011
Negated 6
Speculated 1
Reported most in Abstract
Documents 65
Total Number 66
Disease Relevance 52.89
Pain Relevance 4.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Afp) extracellular space (Afp) extracellular region (Afp)
molecular_function (Afp) cytoplasm (Afp)
Anatomy Link Frequency
liver 12
stomach 3
lymph nodes 2
pancreas 1
germ cell 1
Afp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Analgesic 2 99.14 Very High Very High Very High
Pain 6 98.76 Very High Very High Very High
palliative 30 98.40 Very High Very High Very High
Nicotine 2 97.12 Very High Very High Very High
headache 5 96.24 Very High Very High Very High
abdominal pain 22 95.84 Very High Very High Very High
Paracetamol 4 93.76 High High
agonist 3 90.68 High High
imagery 33 82.16 Quite High
Bile 13 79.04 Quite High
Disease Link Frequency Relevance Heat
Pancreatic Cancer 8 99.98 Very High Very High Very High
Cancer 921 99.96 Very High Very High Very High
Adenocarcinoma 77 99.96 Very High Very High Very High
Stomach Cancer 72 99.96 Very High Very High Very High
Skin Cancer 4 99.96 Very High Very High Very High
Germ Cell And Embryonal Neoplasms 4 99.96 Very High Very High Very High
Liver Cancer 116 99.82 Very High Very High Very High
Cv Unclassified Under Development 38 99.76 Very High Very High Very High
Death 25 99.68 Very High Very High Very High
Metastasis 186 99.66 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We describe a patient with a ruptured and rapidly enlarging secondary tumor of the liver metastasized from an alpha-fetoprotein (AFP)-producing gastric cancer.
Gene_expression (producing) of alpha-fetoprotein in liver associated with stomach cancer and metastasis
1) Confidence 0.78 Published 2005 Journal J Nippon Med Sch Section Abstract Doc Link 16113495 Disease Relevance 0.81 Pain Relevance 0
We describe a patient with a ruptured and rapidly enlarging secondary tumor of the liver metastasized from an alpha-fetoprotein (AFP)-producing gastric cancer.
Gene_expression (producing) of AFP in liver associated with stomach cancer and metastasis
2) Confidence 0.78 Published 2005 Journal J Nippon Med Sch Section Abstract Doc Link 16113495 Disease Relevance 0.81 Pain Relevance 0
We report on a rare hepatoid adenocarcinoma of the stomach producing alpha-fetoprotein (AFP) in five cases.
Gene_expression (producing) of AFP in stomach associated with adenocarcinoma
3) Confidence 0.77 Published 2006 Journal Acta Gastroenterol. Belg. Section Abstract Doc Link 17168134 Disease Relevance 0.49 Pain Relevance 0.07
In recent years, many cases of alpha-fetoprotein-producing gastric cancer (AFPGC) characterized by increased serum levels of alpha-fetoprotein (AFP) and AFP positivity of the gastric cancer have been reported.
Gene_expression (levels) of AFP associated with stomach cancer
4) Confidence 0.76 Published 1996 Journal J. Gastroenterol. Section Abstract Doc Link 9027651 Disease Relevance 0.75 Pain Relevance 0.07
Here we present a case of AFPGC coexistent with a different histological type of gastric cancer: The AFPGC was Borrmann type 1 advanced gastric cancer with multiple liver metastasis and appeared to produce both AFP and des-gamma-carboxy prothrombin (PIVKA-II).
Gene_expression (produce) of AFP in liver associated with metastasis and stomach cancer
5) Confidence 0.76 Published 1996 Journal J. Gastroenterol. Section Abstract Doc Link 9027651 Disease Relevance 0.81 Pain Relevance 0.09
In recent years, many cases of alpha-fetoprotein-producing gastric cancer (AFPGC) characterized by increased serum levels of alpha-fetoprotein (AFP) and AFP positivity of the gastric cancer have been reported.
Gene_expression (levels) of alpha-fetoprotein associated with stomach cancer
6) Confidence 0.76 Published 1996 Journal J. Gastroenterol. Section Abstract Doc Link 9027651 Disease Relevance 0.74 Pain Relevance 0.07
In recent years, many cases of alpha-fetoprotein-producing gastric cancer (AFPGC) characterized by increased serum levels of alpha-fetoprotein (AFP) and AFP positivity of the gastric cancer have been reported.
Gene_expression (producing) of alpha-fetoprotein associated with stomach cancer
7) Confidence 0.76 Published 1996 Journal J. Gastroenterol. Section Abstract Doc Link 9027651 Disease Relevance 0.71 Pain Relevance 0.06
Alpha-fetoprotein and alphal-antritrypsin were detected in about 30% of cells; HepPar1 was present in 15% of cells.
Gene_expression (detected) of Alpha-fetoprotein
8) Confidence 0.75 Published 2008 Journal Virchows Arch. Section Abstract Doc Link 18193278 Disease Relevance 1.08 Pain Relevance 0.12
We report a rare case of pancreatic carcinoma producing alpha-fetoprotein (AFP), showing focal hepatoid differentiation in metastatic lymph nodes.
Gene_expression (producing) of AFP in lymph nodes associated with pancreatic cancer
9) Confidence 0.75 Published 1999 Journal Int. J. Pancreatol. Section Abstract Doc Link 10566157 Disease Relevance 0.59 Pain Relevance 0.09
Immunohistochemical analysis showed that the tumor cells expressed AFP, alpha 1-antitrypsin (AT) and albumin.
Gene_expression (expressed) of AFP associated with cancer
10) Confidence 0.75 Published 1999 Journal Int. J. Pancreatol. Section Abstract Doc Link 10566157 Disease Relevance 0.71 Pain Relevance 0.08
We report a rare case of pancreatic carcinoma producing alpha-fetoprotein (AFP), showing focal hepatoid differentiation in metastatic lymph nodes.
Gene_expression (producing) of alpha-fetoprotein in lymph nodes associated with pancreatic cancer
11) Confidence 0.75 Published 1999 Journal Int. J. Pancreatol. Section Abstract Doc Link 10566157 Disease Relevance 0.59 Pain Relevance 0.09
[Significant effects on alpha-fetoprotein (AFP) concentration in maternal serum in pregnancy].
Gene_expression (concentration) of AFP associated with analgesic
12) Confidence 0.67 Published 1991 Journal Zentralbl Gynakol Section Title Doc Link 1711749 Disease Relevance 0.09 Pain Relevance 0.29
We suggest that the introduction of highly sensitive EIAs for the detection of AFP will require a reevaluation of AFP as a prognostic marker in acute nonneoplastic liver disease.
Gene_expression (detection) of AFP in liver associated with liver disease
13) Confidence 0.66 Published 2005 Journal Hepatology Section Abstract Doc Link 15690478 Disease Relevance 0.37 Pain Relevance 0.22
Alpha-fetoprotein-producing urachal adenocarcinoma.
Gene_expression (producing) of Alpha-fetoprotein associated with adenocarcinoma
14) Confidence 0.61 Published 1991 Journal Acta Pathol. Jpn. Section Title Doc Link 1713733 Disease Relevance 0.77 Pain Relevance 0.08
Ruptured metastatic liver tumor from an alpha-fetoprotein-producing gastric cancer.
Gene_expression (producing) of alpha-fetoprotein in liver associated with liver cancer and stomach cancer
15) Confidence 0.60 Published 2005 Journal J Nippon Med Sch Section Title Doc Link 16113495 Disease Relevance 1.21 Pain Relevance 0.06
She had high serum levels of alpha fetoprotein (AFP) and CA125.
Gene_expression (levels) of AFP
16) Confidence 0.58 Published 2006 Journal Int. J. Gynecol. Cancer Section Abstract Doc Link 16803543 Disease Relevance 0.73 Pain Relevance 0.10
At the same time they examined possible sites of AFP production.
Gene_expression (production) of AFP
17) Confidence 0.55 Published 1979 Journal Acta Hepatogastroenterol (Stuttg) Section Abstract Doc Link 90439 Disease Relevance 0.42 Pain Relevance 0.08
Hepatitis B surface antigen (HBsAg) and anti-hepatitis C antibody were negative and serum alpha-fetoprotein (AFP) was within the normal limit.
Neg (negative) Gene_expression (negative) of AFP associated with hepatitis b virus infection and hepatitis
18) Confidence 0.53 Published 1996 Journal J. Gastroenterol. Hepatol. Section Abstract Doc Link 8792309 Disease Relevance 0.94 Pain Relevance 0.09
The cancer cells were rich in glycogen and were immunoreactive diffusely for AFP and focally for CEA.
Gene_expression (immunoreactive) of AFP associated with cancer
19) Confidence 0.53 Published 1991 Journal Acta Pathol. Jpn. Section Abstract Doc Link 1713733 Disease Relevance 0.82 Pain Relevance 0.08
Our experience together with what has been reported in literature suggest that the course of hepatoid adenocarcinoma of the stomach is more aggressive than an ordinary adenocarcinoma and that from a diagnostic point of view distinction from an adenocarcinoma may be accomplished histochemically and by measuring serum AFP levels.
Gene_expression (levels) of AFP in stomach associated with adenocarcinoma
20) Confidence 0.52 Published 2006 Journal Acta Gastroenterol. Belg. Section Abstract Doc Link 17168134 Disease Relevance 0.66 Pain Relevance 0.08

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