INT74546

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Context Info
Confidence 0.47
First Reported 1998
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.16
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Tecr) cytoplasm (Tecr)
Anatomy Link Frequency
colon 2
Tecr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 9 98.88 Very High Very High Very High
anesthesia 2 81.52 Quite High
cytokine 6 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 3 87.28 High High
Sepsis 20 5.00 Very Low Very Low Very Low
Adult Respiratory Distress Syndrome 14 5.00 Very Low Very Low Very Low
INFLAMMATION 9 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Hypoxia 2 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low
Respiratory Tract Infection 2 5.00 Very Low Very Low Very Low
Heart Rate Under Development 2 5.00 Very Low Very Low Very Low
Pneumonia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The phorbol ester and protein kinase C (PKC) activator, phorbol dibutyrate (PDBU), was observed to produce an over 100% elevation of Iscc but only a small yet significant 20-30% decrease of TER across rat distal colon.
Positive_regulation (elevation) of Gene_expression (produce) of TER in colon associated with kinase c
1) Confidence 0.47 Published 1998 Journal Dig. Dis. Sci. Section Abstract Doc Link 9539661 Disease Relevance 0 Pain Relevance 0.37
Treatment of sham monolayers with ouabain, not amiloride, significantly improved TER in sham monolayers, while neither treatment altered TER in 2CLP monolayers.
Neg (neither) Positive_regulation (improved) of Neg (neither) Gene_expression (improved) of TER
2) Confidence 0.14 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2892473 Disease Relevance 0.16 Pain Relevance 0

General Comments

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