INT74674

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.67
First Reported 1997
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 8
Disease Relevance 1.00
Pain Relevance 3.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TAC1) extracellular region (TAC1) plasma membrane (TAC1)
cell-cell signaling (TAC1)
Anatomy Link Frequency
neurons 2
blood 1
macrophages 1
monocytes 1
spinal cord 1
TAC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 129 100.00 Very High Very High Very High
Dopamine 3 100.00 Very High Very High Very High
Central grey 11 99.82 Very High Very High Very High
Spinal cord 9 99.72 Very High Very High Very High
adenocard 11 99.18 Very High Very High Very High
Neuropeptide 4 98.40 Very High Very High Very High
Pain 7 89.60 High High
projection neuron 3 88.16 High High
Nucleus accumbens 2 86.52 High High
orphanin 3 75.00 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 11 99.82 Very High Very High Very High
Lung Cancer 4 93.28 High High
Pain 4 76.40 Quite High
Nociception 1 27.28 Quite Low
INFLAMMATION 18 5.00 Very Low Very Low Very Low
Nicotine Addiction 6 5.00 Very Low Very Low Very Low
Asthma 6 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Anaplastic Astrocytoma 4 5.00 Very Low Very Low Very Low
Occupational Lung Diseases 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NST-responsive CeA(M)-PAG neurons contain CRF or substance P mRNA.
Transcription (contain) of substance P in neurons associated with central grey and substance p
1) Confidence 0.67 Published 2009 Journal Mol. Cell. Neurosci. Section Abstract Doc Link 18930828 Disease Relevance 0.91 Pain Relevance 1.04
The former two neuropeptides showed a widespread distribution throughout the whole spinal cord, whereas the distribution of neurokinin B was more restricted.
Transcription (distribution) of neurokinin B in spinal cord associated with neuropeptide and spinal cord
2) Confidence 0.65 Published 2005 Journal Arch Ital Biol Section Abstract Doc Link 15844667 Disease Relevance 0 Pain Relevance 0.35
Using the RT-PCR assay, preprotachykinin-A (substance P) mRNA is detected in human peripheral blood-isolated monocytes and macrophages.
Transcription (detected) of substance P in macrophages associated with substance p
3) Confidence 0.52 Published 1997 Journal J. Immunol. Section Abstract Doc Link 9548509 Disease Relevance 0 Pain Relevance 0.25
Using reverse transcribed polymerase chain reaction (RT-PCR) assay, preprotachykinin-A (substance-P) mRNA is detected in human peripheral blood-isolated lymphocytes.
Transcription (detected) of substance-P in blood
4) Confidence 0.52 Published 1998 Journal J. Neuroimmunol. Section Abstract Doc Link 9655475 Disease Relevance 0 Pain Relevance 0.30
Virtually all adenosine A2A receptor mRNA-containing neurons co-expressed dopamine D2 receptor mRNA, whereas only very few adenosine A2A receptor mRNA containing neurons co-expressed dopamine D1 receptor or substance P mRNAs.
Transcription (expressed) of substance P in neurons associated with dopamine, adenocard and substance p
5) Confidence 0.52 Published 1998 Journal J. Comp. Neurol. Section Abstract Doc Link 9721905 Disease Relevance 0 Pain Relevance 0.71
In a previous study, Pinto et al. showed in a human total mRNA master panel (BD Biosciences Clontech) that TAC1 and TAC3 mRNAs were undetectable in the lung, but they observed a low expression of these transcripts in samples of human bronchi obtained from patients who had undergone lobectomy or pneumectomy for lung carcinoma, a high expression being observed in pulmonary arteries [48].
Transcription (undetectable) of TAC1 in lung associated with lung cancer
6) Confidence 0.49 Published 2010 Journal Respir Res Section Body Doc Link PMC2959027 Disease Relevance 0.09 Pain Relevance 0.11
In human bronchi, TAC4, TACR1 and TACR2 mRNAs were found in all samples whereas TAC1 and TACR3 mRNAs were not detected (fig. 1).
Transcription (detected) of TAC1
7) Confidence 0.49 Published 2010 Journal Respir Res Section Body Doc Link PMC2959027 Disease Relevance 0 Pain Relevance 0
Using the RT-PCR assay, preprotachykinin-A (substance P) mRNA is detected in human peripheral blood-isolated monocytes and macrophages.
Transcription (detected) of substance P in monocytes associated with substance p
8) Confidence 0.18 Published 1997 Journal J. Immunol. Section Abstract Doc Link 9548509 Disease Relevance 0 Pain Relevance 0.25

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox