INT74737

Context Info Confidence 0.29 First Reported 1998 Last Reported 1998 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.19 Pain Relevance 0.04

extracellular region (Penk) aging (Fos) nucleolus (Fos) nucleus (Fos) DNA binding (Fos) transcription factor binding (Fos)

Fos (Rattus norvegicus) Penk (Rattus norvegicus)

Pain Link Frequency Relevance Heat Hippocampus 1 75.00 nMDA receptor 1 31.20 Enkephalin 1 25.00

Disease Link Frequency Relevance Heat Convulsion 4 70.00 Targeted Disruption 1 65.76

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

For a long time Fos has been proposed to play some role in regulation of the proenkephalin (PENK) and prodynorphin (PDYN) gene expression.

Fos Regulation (regulation) of proenkephalin

1) Confidence 0.29 Published 1998 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 9555037 Disease Relevance 0.19 Pain Relevance 0.04

General Comments

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