INT74781

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Context Info
Confidence 0.39
First Reported 1998
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 2.75
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (JAG1) structural molecule activity (JAG1) plasma membrane (JAG1)
Anatomy Link Frequency
leukocytes 1
JAG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 56 90.84 High High
spinal inflammation 3 88.72 High High
anesthesia 1 86.36 High High
Arthritis 3 85.92 High High
imagery 7 80.32 Quite High
agonist 4 75.00 Quite High
aspirin 2 69.04 Quite High
backache 2 65.76 Quite High
chemokine 4 62.92 Quite High
cytokine 4 56.20 Quite High
Disease Link Frequency Relevance Heat
Alagille Syndrome 83 100.00 Very High Very High Very High
Pressure And Volume Under Development 5 99.68 Very High Very High Very High
INFLAMMATION 64 90.84 High High
Low Back Pain 5 88.72 High High
Obesity 8 88.68 High High
Seronegative Spondarthritis 1 86.64 High High
Osteoporosis 18 78.32 Quite High
Humeral Fractures 2 76.76 Quite High
Cancer 6 66.00 Quite High
Multiple Sclerosis 2 65.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Insertion of the Pentax-AWS was unaffected by the swelling and tracheal intubation was successful within 10 sec.
Neg (unaffected) Regulation (unaffected) of Pentax-AWS associated with pressure and volume under development and alagille syndrome
1) Confidence 0.39 Published 2010 Journal Masui Section Abstract Doc Link 20420136 Disease Relevance 0.70 Pain Relevance 0.13
Another striking finding was the up-regulation of JAG1 consequent to AnxA1.
Regulation (regulation) of JAG1
2) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2941452 Disease Relevance 0.19 Pain Relevance 0.09
We have recently demonstrated that homocysteine can modify HLA class I Ags and induce homocysteine-specific CTL (Hom-CTL) responses in humans.
Regulation (modify) of Ags associated with alagille syndrome
3) Confidence 0.26 Published 1998 Journal J. Immunol. Section Abstract Doc Link 9558075 Disease Relevance 0.28 Pain Relevance 0.13
Up-regulation of this gene, as well as JAG1 (and down-regulation of JAM3), was confirmed using real time PCR both with transfected HEK293 cells and human peripheral blood leukocytes.
Regulation (regulation) of JAG1 in leukocytes
4) Confidence 0.14 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2941452 Disease Relevance 0.28 Pain Relevance 0.21
The authors of this study, therefore, evaluated the efficacy of using AHD, WOD, and RPD separately and in combination to screen for undiagnosed vertebral fractures in middle-aged and elderly Japanese women.


Regulation (efficacy) of AHD associated with alagille syndrome
5) Confidence 0.13 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2613887 Disease Relevance 0.61 Pain Relevance 0
No differences in AHD values were identified between the two groups.
Neg (No) Regulation (values) of AHD associated with alagille syndrome
6) Confidence 0.13 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2613887 Disease Relevance 0.61 Pain Relevance 0.07
INTERVENTIONS: The Constant score was determined preoperatively; acromial shape (type I, flat; type II, curved; and type III, hooked) was evaluated on preoperative outlet view radiographs and oblique sagittal T1-weighted MRIs; AHD was evaluated on preoperative anteroposterior radiographs and oblique coronal T1-weighted MRIs.
Regulation (evaluated) of AHD
7) Confidence 0.08 Published 2009 Journal Clin J Sport Med Section Body Doc Link 19451760 Disease Relevance 0.08 Pain Relevance 0

General Comments

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