INT74863

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Context Info
Confidence 0.50
First Reported 1998
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.16
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (PRDX1) mitochondrion (PRDX1) oxidoreductase activity (PRDX1)
nucleus (PRDX1) cytoplasm (PRDX1)
Anatomy Link Frequency
B lymphocytes 1
PRDX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
peptic ulcer disease 1 97.16 Very High Very High Very High
Osteoarthritis 27 5.00 Very Low Very Low Very Low
cytokine 10 5.00 Very Low Very Low Very Low
Inflammation 9 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ulcers 4 99.56 Very High Very High Very High
Stress 9 99.00 Very High Very High Very High
Lymphatic System Cancer 122 97.32 Very High Very High Very High
Multiple Myeloma 7 96.68 Very High Very High Very High
Disease 27 96.64 Very High Very High Very High
Adhesions 1 96.16 Very High Very High Very High
Cancer 42 82.28 Quite High
Infection 10 75.00 Quite High
Sprains And Strains 5 68.08 Quite High
T-cell Lymphoma 21 63.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Three of these proteins were found to be positively modulated only by GS: peroxiredoxin-1 (PRDX1: redox process), HSPB1 (stress response) and collagen alpha-1(VI) chain precursor (CO6A1: cell adhesion).
Gene_expression (modulated) of PRDX1 associated with stress and adhesions
1) Confidence 0.50 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945029 Disease Relevance 0.38 Pain Relevance 0
The possession of the cytotoxin-associated gene (cagA) of Helicobacter pylori is thought to be highly associated with peptic ulcer disease.
Gene_expression (possession) of cytotoxin-associated gene associated with peptic ulcer disease, ulcers and disease
2) Confidence 0.01 Published 1998 Journal J. Gastroenterol. Hepatol. Section Abstract Doc Link 9570243 Disease Relevance 0.62 Pain Relevance 0.10
Damasi et al., after demonstrating that peroxiredoxin I (PrdxI) is expressed in plasma cells but not in B lymphocytes, analyzed eight cases of PBL and nine of MM by immunohistochemistry.
Neg (not) Gene_expression (expressed) of peroxiredoxin I in B lymphocytes associated with lymphatic system cancer and multiple myeloma
3) Confidence 0.01 Published 2008 Journal J Hematop Section Body Doc Link PMC2713479 Disease Relevance 1.16 Pain Relevance 0

General Comments

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