INT74941

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Context Info
Confidence 0.08
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.48
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IL1B) signal transduction (IL1B) extracellular space (IL1B)
aging (IL1B) extracellular region (IL1B) plasma membrane (PTGER2)
Anatomy Link Frequency
HGF 4
IL1B (Homo sapiens)
PTGER2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 8 90.32 High High
cytokine 2 90.32 High High
COX2 2 25.00 Low Low
cOX1 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Ulcers 4 86.88 High High
INFLAMMATION 4 83.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IND significantly reduced both basal and IL-1 beta-induced PGE2 release and HGF production.
IL-1 Positive_regulation (induced) of Gene_expression (production) of PGE2 in HGF
1) Confidence 0.08 Published 1998 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 9571196 Disease Relevance 0.23 Pain Relevance 0.36
Among various potential stimulants tested, interleukin-1 beta (IL-1 beta) dramatically increased PGE2 production and significantly stimulated HGF production.
interleukin-1 beta Positive_regulation (increased) of Gene_expression (production) of PGE2 in HGF
2) Confidence 0.07 Published 1998 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 9571196 Disease Relevance 0.25 Pain Relevance 0.36

General Comments

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