INT74977

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Context Info
Confidence 0.41
First Reported 1998
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 4.66
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (FGFR1) extracellular region (FGFR1) cytoplasmic membrane-bounded vesicle (FGFR1)
plasma membrane (FGFR1) nucleus (FGFR1) cytoplasm (FGFR1)
Anatomy Link Frequency
artery 2
blood 1
brain 1
fibroblast 1
FGFR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
colic 8 99.48 Very High Very High Very High
Substantia nigra 9 97.92 Very High Very High Very High
abdominal pain 3 94.84 High High
cINOD 10 85.60 High High
peptic ulcer disease 1 77.48 Quite High
midbrain 11 50.00 Quite Low
Inflammation 1 48.96 Quite Low
COX-2 inhibitor 1 37.84 Quite Low
imagery 49 5.00 Very Low Very Low Very Low
depression 28 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aneurism 10 99.80 Very High Very High Very High
Ulcers 12 99.58 Very High Very High Very High
Ruptured Aneurysm 2 99.52 Very High Very High Very High
Abdominal Cramps 8 99.48 Very High Very High Very High
Rupture 2 97.64 Very High Very High Very High
Cancer 41 96.48 Very High Very High Very High
Post-traumatic Stress Disorder 62 96.32 Very High Very High Very High
Abdominal Pain 3 94.84 High High
Apoptosis 12 93.48 High High
Ovarian Cancer 63 86.64 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This report describes a case of a middle-colic artery aneurysm that was associated with SAM.
SAM Binding (associated) of in artery associated with colic and aneurism
1) Confidence 0.41 Published 2009 Journal Surg. Today Section Abstract Doc Link 19198994 Disease Relevance 0.99 Pain Relevance 0.27
A rupture of a middle-colic artery aneurysm was diagnosed by computed tomography, and angiography showed that it may have been associated with SAM.
SAM Binding (associated) of in artery associated with colic, rupture and aneurism
2) Confidence 0.41 Published 2009 Journal Surg. Today Section Abstract Doc Link 19198994 Disease Relevance 0.99 Pain Relevance 0.27
FGFBP1 and FGFR1 interact with fibroblast growth factors FGF1 and FGF2, and it has been suggested that the fibroblast growth factors could serve as the angiogenic switch in human cancer [41–43].
FGFR1 Binding (interact) of in fibroblast associated with cancer
3) Confidence 0.32 Published 2009 Journal PLoS Medicine Section Body Doc Link PMC2634794 Disease Relevance 0.92 Pain Relevance 0
In experimental models, peptic ulcer healing can also be accelerated by oral administration of basic fibroblast growth factor, which increases angiogenesis in the ulcer bed, or by nitric oxide-releasing compounds, which improve gastric blood flow.
basic fibroblast growth factor Binding (accelerated) of in blood associated with ulcers
4) Confidence 0.13 Published 1998 Journal Am. J. Med. Section Abstract Doc Link 9572320 Disease Relevance 1.15 Pain Relevance 0.38
In addition, the receptor for FGF-20, FGFR1c, is highly expressed by TH-positive neurons in the substantia nigra and is lower in other brain regions (Ohmachi et al., 2003).
FGFR1c Binding (receptor) of in brain associated with substantia nigra
5) Confidence 0.04 Published 2007 Journal Frontiers in Neuroanatomy Section Body Doc Link PMC2525922 Disease Relevance 0.20 Pain Relevance 0.10
The SAM system holds low-level representations tightly bound to their sensory and affective qualities.
SAM Binding (bound) of
6) Confidence 0.02 Published 2010 Journal Psychol Rev Section Body Doc Link PMC2834572 Disease Relevance 0.41 Pain Relevance 0

General Comments

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