INT75033

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Context Info
Confidence 0.00
First Reported 1998
Last Reported 1998
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.08

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mitochondrion (Cyp11b1)
Anatomy Link Frequency
liver 2
Slc6a14 (Rattus norvegicus)
Cyp11b1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 3 79.40 Quite High
Disease Link Frequency Relevance Heat
Injury 2 81.04 Quite High
Hepatotoxicity 2 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Western immunoblotting analyses revealed that ATB treatment (50 mg/kg/day for 5 days) failed to alter cytochrome P4501A2, P4502B1/2 and P4502E1 levels in the liver, whereas the expression of P4502C11 was reduced approximately 50% by ATB. 3.
ATB Neg (failed) Negative_regulation (reduced) of Gene_expression (expression) of P4502C11 in liver
1) Confidence 0.00 Published 1998 Journal Xenobiotica Section Abstract Doc Link 9574820 Disease Relevance 0.08 Pain Relevance 0.08

General Comments

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