INT75148

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Context Info
Confidence 0.00
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (ADRA1B) nucleus (ZNF594) intracellular (ZNF594)
plasma membrane (ADRA1B) DNA binding (ZNF594) cell-cell signaling (ADRA1B)
ADRA1B (Homo sapiens)
ZNF594 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 2 82.64 Quite High
Analgesic 3 75.00 Quite High
Nicotine 1 64.80 Quite High
dorsal root ganglion 1 53.92 Quite High
Pain 1 36.32 Quite Low
Morphine 1 33.84 Quite Low
Antinociceptive 1 31.76 Quite Low
Spinal cord 1 25.00 Low Low
Pain management 1 25.00 Low Low
Calcitonin gene-related peptide 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 3 58.56 Quite High
Pain 2 36.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ABT-594 has weak affinity in binding assays for adrenoreceptor subtypes alpha-1B (Ki = 890 nM), alpha-2B (Ki = 597 nM) and alpha-2C (Ki = 342 nM), and it has negligible affinity (Ki > 1000 nM) for approximately 70 other receptors, enzyme and transporter binding sites.
alpha-1B Binding (affinity) of ABT-594
1) Confidence 0.00 Published 1998 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 9580626 Disease Relevance 0.16 Pain Relevance 0.18

General Comments

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