INT75150

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Context Info
Confidence 0.00
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (ZNF594, ZNF594) DNA binding (ZNF594, ZNF594) nucleus (ZNF594, ZNF594)
endosome (CALCRL) endoplasmic reticulum (CALCRL) signal transducer activity (CALCRL)
Anatomy Link Frequency
brain 2
ZNF594 (Homo sapiens)
CALCRL (Homo sapiens)
ZNF594 (Homo sapiens)
Pain Link Frequency Relevance Heat
Analgesic 3 91.76 High High
Pain 1 78.44 Quite High
Morphine 1 75.96 Quite High
Antinociceptive 1 73.88 Quite High
agonist 2 73.04 Quite High
Spinal cord 1 25.00 Low Low
dorsal root ganglion 1 25.00 Low Low
Nicotine 1 25.00 Low Low
Pain management 1 25.00 Low Low
Calcitonin gene-related peptide 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Pain 2 78.44 Quite High
Ganglion Cysts 3 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ABT-594 is a potent inhibitor of the binding of [3H](-)-cytisine to alpha 4 beta 2 neuronal nAChRs (Ki = 37 pM, rat brain; Ki = 55 pM, transfected human receptor).
ABT-594 Negative_regulation (inhibitor) of receptor Binding (binding) of ABT-594 in brain
1) Confidence 0.00 Published 1998 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 9580626 Disease Relevance 0.08 Pain Relevance 0.39

General Comments

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