INT75169

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Context Info
Confidence 0.67
First Reported 1998
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.87
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (GGT2) plasma membrane (GGT2) transferase activity, transferring acyl groups (GGT2)
cellular_component (GGT2)
Anatomy Link Frequency
liver 1
GGT2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 1 95.92 Very High Very High Very High
sNRI 26 84.80 Quite High
Duloxetine 24 77.04 Quite High
headache 4 47.68 Quite Low
sSRI 28 39.68 Quite Low
depression 28 5.00 Very Low Very Low Very Low
antidepressant 12 5.00 Very Low Very Low Very Low
Pain 12 5.00 Very Low Very Low Very Low
Serotonin 8 5.00 Very Low Very Low Very Low
Dopamine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 15 99.98 Very High Very High Very High
Disorder Of Lipid Metabolism 12 99.32 Very High Very High Very High
Vomiting 20 88.76 High High
Reprotox - General 3 2 86.72 High High
Body Weight 1 81.88 Quite High
Suicidal Behaviour 4 81.24 Quite High
Death 2 69.60 Quite High
Depression 84 65.20 Quite High
Recurrence 14 63.36 Quite High
Diarrhoea 2 49.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results included decreased bilirubin and increased gamma glutamyl transferase (GGT), alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT).
Positive_regulation (increased) of GGT
1) Confidence 0.67 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695227 Disease Relevance 0.54 Pain Relevance 0
Laboratory tests showed decrease in bilirubin levels, and increase in GGT, ALP, AST, ALT, total cholesterol, HDL, LDL, and triglycerides, demonstrating potential effects on the metabolic system.
Positive_regulation (increase) of GGT associated with disorder of lipid metabolism
2) Confidence 0.67 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695227 Disease Relevance 0.42 Pain Relevance 0.08
Streptozotocin-induced diabetes increases gamma-glutamyltranspeptidase activity but not expression in rat liver.
Neg (not) Positive_regulation (increases) of gamma-glutamyltranspeptidase in liver associated with diabetes mellitus
3) Confidence 0.13 Published 1998 Journal J. Biochem. Mol. Toxicol. Section Title Doc Link 9580874 Disease Relevance 0.92 Pain Relevance 0.10

General Comments

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