INT7524

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Context Info
Confidence 0.74
First Reported 1982
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 9
Total Number 9
Disease Relevance 3.45
Pain Relevance 5.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Kitl) extracellular region (Kitl) cell adhesion (Kitl)
plasma membrane (Kitl) cytoskeleton (Kitl) cytoplasm (Kitl)
Anatomy Link Frequency
spinal 1
stem cell 1
lacrimal 1
Kitl (Mus musculus)
Pain Link Frequency Relevance Heat
Central grey 32 100.00 Very High Very High Very High
Clonidine 4 100.00 Very High Very High Very High
spinal dorsal horn 3 100.00 Very High Very High Very High
Serotonin 3 100.00 Very High Very High Very High
Enkephalin 20 99.96 Very High Very High Very High
Inflammation 5 99.92 Very High Very High Very High
narcan 4 99.92 Very High Very High Very High
Pain 4 99.42 Very High Very High Very High
Morphine 10 98.72 Very High Very High Very High
lidocaine 1 96.44 Very High Very High Very High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 32 100.00 Very High Very High Very High
Cytomegalovirus Infection 6 100.00 Very High Very High Very High
Disorders Of The Lacrimal System 5 99.98 Very High Very High Very High
INFLAMMATION 3 99.08 Very High Very High Very High
Pain 6 98.36 Very High Very High Very High
Ocular Toxicity (including Many Sub-types) 1 76.80 Quite High
Death 11 76.76 Quite High
Immunization 2 75.00 Quite High
Apoptosis 9 73.72 Quite High
Hematological Disease 10 48.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of a secondary amine (ketamine), tertiary amines (dibucaine, lidocaine, marcaine, propanidid, diazepam and chlorpromazine) and a quaternary amine (tetraethylammonium bromide, TEA) on mouse 3T3 cell agglutination by concanavalin A (Con A), on patch formation of Con A receptors on the cell surface, and on paracrystal formation by vinblastine in cytoplasm were studied.
Localization (formation) of Con associated with ketamine and lidocaine
1) Confidence 0.74 Published 1982 Journal Tohoku J. Exp. Med. Section Abstract Doc Link 6808705 Disease Relevance 0 Pain Relevance 0.18
In mice lacrimal gland, Met, and NE elicited dose-related lacrimal secretions, however, Xyl and Clo had no such reaction.
Localization (secretions) of Clo in lacrimal associated with disorders of the lacrimal system and clonidine
2) Confidence 0.23 Published 1992 Journal Zhongguo Yao Li Xue Bao Section Abstract Doc Link 1350880 Disease Relevance 0.45 Pain Relevance 0.49
ConGrase was released at the 44 th Annual Meeting of the Japan Society of Anesthesiology, and is distributed freely.
Localization (released) of ConGrase
3) Confidence 0.15 Published 1998 Journal Masui Section Abstract Doc Link 9834602 Disease Relevance 0 Pain Relevance 0.06
Purified KSL cells from C57BL/6 bone marrow were irradiated with 3 Gy and cultured with 5 nM of rhGH in the presence of thrombopoietin, stem cell factor, and Flt3 ligand (TSF).
Localization (presence) of stem cell factor in stem cell
4) Confidence 0.12 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2886847 Disease Relevance 0.21 Pain Relevance 0
The immune responses of mice injected with plasmids VR-gB and VR-gB Delta tm expressing the full-length membrane-anchored, or secreted forms of human cytomegalovirus (HCMV)-glycoprotein B (gB), respectively, and VR-pp65 expressing the HCMV-phosphoprotein 65 (pp65) were analyzed.
Localization (secreted) of gB associated with cytomegalovirus infection
5) Confidence 0.11 Published 2001 Journal Vaccine Section Abstract Doc Link 11427273 Disease Relevance 0.45 Pain Relevance 0.09
The changes in OFQ-immunoreactivity (OFQ-ir) content and release of cerebroventricular perfusate, periaqueductal gray (PAG) and amygadala of chronic morphine tolerant rats were measured with radioimmunoassay (RIA).
Localization (release) of periaqueductal gray associated with central grey and morphine
6) Confidence 0.01 Published 1999 Journal Sheng Li Xue Bao Section Abstract Doc Link 11498977 Disease Relevance 0.20 Pain Relevance 0.65
The release of serotonin in rat spinal dorsal horn and periaqueductal gray following carrageenan inflammation.
Localization (release) of periaqueductal gray in spinal associated with inflammation, spinal dorsal horn, central grey and serotonin
7) Confidence 0.00 Published 2000 Journal Neuroreport Section Title Doc Link 11095514 Disease Relevance 0.81 Pain Relevance 1.24
Previous study has proven that arginine vasopressin (AVP) enhances periaqueductal gray (PAG) secreting enkephalin and endorphin in vivo in the rat.
Localization (secreting) of periaqueductal gray associated with enkephalin and central grey
8) Confidence 0.00 Published 2006 Journal Brain Res. Bull. Section Abstract Doc Link 17113946 Disease Relevance 0.50 Pain Relevance 1.06
Arginine vasopressin induces periaqueductal gray release of enkephalin and endorphin relating to pain modulation in the rat.
Localization (release) of periaqueductal gray associated with pain, enkephalin and central grey
9) Confidence 0.00 Published 2007 Journal Regul. Pept. Section Title Doc Link 17341433 Disease Relevance 0.83 Pain Relevance 1.73

General Comments

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