INT75311

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Context Info
Confidence 0.77
First Reported 1998
Last Reported 2009
Negated 2
Speculated 0
Reported most in Abstract
Documents 5
Total Number 6
Disease Relevance 5.13
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
leukocyte 1
T-cell 1
Cd79a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
medulla 1 95.20 Very High Very High Very High
imagery 1 84.96 Quite High
backache 1 81.20 Quite High
rheumatoid arthritis 5 80.20 Quite High
abdominal pain 1 75.24 Quite High
Pain 3 75.00 Quite High
headache 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 16 99.76 Very High Very High Very High
T-cell Lymphoma 1 97.88 Very High Very High Very High
Leukemia 24 96.92 Very High Very High Very High
Acute Myeloid Leukemia 48 94.88 High High
Necrosis 1 92.72 High High
Lymphatic System Cancer 9 90.72 High High
Acute Monocytic Leukemia 2 89.12 High High
Rhinitis 1 88.72 High High
Malignant Neoplastic Disease 1 87.48 High High
Cv General 2 Under Development 2 86.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Aberrant expression of CD79a has been reported in neoplastic cells in peripheral T cell lymphoma, T-cell acute lymphoblastic leukemia and acute myeloid leukemia (especially those with t(8;21)).
Gene_expression (expression) of CD79a in T-cell associated with t-cell lymphoma and leukemia
1) Confidence 0.77 Published 2007 Journal Haematologica Section Abstract Doc Link 17550863 Disease Relevance 0.44 Pain Relevance 0.07
Flow cytometric immunophenotyping demonstrated expression of HLA-DR+/CD64+, CD36+/CD116+, CD14+/-, cCD68+, CD33++, CD13+/-, CD4+ and non expression of CD34, CD79a, CD20, CD10 and, CD3.
Gene_expression (expression) of CD79a
2) Confidence 0.39 Published 2006 Journal J Occup Med Toxicol Section Body Doc Link PMC1544343 Disease Relevance 0.57 Pain Relevance 0
Flow cytometric immunophenotyping demonstrated expression of HLA-DR+/CD64+, CD36+/CD116+, CD14+/-, cCD68+, CD33++, CD13+/-, CD4+ and non expression of CD34, CD79a, CD20, CD10 and, CD3.
Gene_expression (expression) of CD79a
3) Confidence 0.30 Published 2006 Journal J Occup Med Toxicol Section Body Doc Link PMC1544343 Disease Relevance 0.63 Pain Relevance 0
Immunohistochemically, tumor cells were positive for CD20 and CD79a.
Gene_expression (positive) of CD79a associated with cancer
4) Confidence 0.27 Published 1998 Journal Pathol. Int. Section Abstract Doc Link 9589469 Disease Relevance 1.48 Pain Relevance 0.36
Immunohistochemically, the tumor cells were positive for CD20 and CD79a and negative for CD3, CD10, and cyclin D1.
Neg (negative) Gene_expression (positive) of CD79a associated with cancer
5) Confidence 0.20 Published 2009 Journal Hepatogastroenterology Section Abstract Doc Link 19760945 Disease Relevance 1.31 Pain Relevance 0.08
All were negative for leukocyte common antigen, Tdt, CD3, CD20, CD79, CK20, pankeratin, epithelial membrane antigen, chromogranin, neurofilament protein, carcinoembryonic antigen, desmin, actin, diffuse S100 protein, and HMB45.
Neg (negative) Gene_expression (negative) of CD79 in leukocyte
6) Confidence 0.00 Published 2007 Journal Ann Diagn Pathol Section Abstract Doc Link 17498589 Disease Relevance 0.72 Pain Relevance 0.07

General Comments

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