INT75314

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Context Info
Confidence 0.26
First Reported 1998
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.42
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Ghr) extracellular space (Ghr) extracellular region (Ghr)
plasma membrane (Ghr) nucleus (Ghr) cytoplasm (Ghr)
Anatomy Link Frequency
skeletal muscle 2
Ghr (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 6 73.72 Quite High
Inflammatory response 1 29.88 Quite Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 7 89.36 High High
Injury 2 86.60 High High
Sepsis 2 86.28 High High
Weight Loss 7 84.00 Quite High
Hypoglycemia 5 74.68 Quite High
Hutchinson-gilford Progeria Syndrome 3 39.80 Quite Low
Aging 29 38.48 Quite Low
INFLAMMATION 1 29.48 Quite Low
Obesity 1 11.36 Low Low
Lipodystrophy 1 6.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, the normal serum GH levels together with the significant systemic down regulation of GH receptor gene expression likely point to growth hormone resistance in 15-d-old Csbm/m/Xpa?
Regulation (regulation) of Gene_expression (expression) of GH receptor
1) Confidence 0.26 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1698505 Disease Relevance 0.16 Pain Relevance 0
The aim of this study was to investigate the effect of GH treatment on expression of the IGF-I gene and GH receptor (GHR) gene in skeletal muscle after major surgery.
Regulation (effect) of Gene_expression (expression) of GHR in skeletal muscle
2) Confidence 0.06 Published 1998 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 9589657 Disease Relevance 0.26 Pain Relevance 0
No statistically significant changes were seen in GHR expression.
Regulation (changes) of Gene_expression (expression) of GHR
3) Confidence 0.04 Published 1998 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 9589657 Disease Relevance 0 Pain Relevance 0.15

General Comments

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