INT75370

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Context Info
Confidence 0.00
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 1.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Hrh1, RGD735065) cytoplasm (Hrh1, RGD735065) signal transduction (Hrh1)
nucleus (Hrh1) signal transducer activity (Hrh1)
Hrh1 (Mus musculus)
RGD735065 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Serotonin 1 99.82 Very High Very High Very High
gABA 1 98.76 Very High Very High Very High
antinociception 5 97.96 Very High Very High Very High
Hyperalgesia 3 94.56 High High
Glutamate 6 93.72 High High
Pain 3 92.76 High High
qutenza 4 92.24 High High
Neuronal nitric oxide synthase 1 86.64 High High
Analgesic 2 79.68 Quite High
Antinociceptive 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Bordatella Infection 2 100.00 Very High Very High Very High
Hyperalgesia 3 94.56 High High
Pain 1 92.76 High High
Sleep Disorders 1 75.88 Quite High
INFLAMMATION 1 72.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Dipyrone antinociception seems unlikely to involve an interaction with the L-arginine-nitric oxide pathway, serotonin system, activation of Gi protein sensitive to pertussis toxin. interaction of ATP-sensitive K+ channels, GABA(B) receptors, or the release of endogenous glucocorticoids.
Positive_regulation (activation) of pertussis toxin Binding (interaction) of Gi protein associated with antinociception, gaba, bordatella infection and serotonin
1) Confidence 0.00 Published 1998 Journal Eur. J. Pharmacol. Section Abstract Doc Link 9592021 Disease Relevance 0.56 Pain Relevance 1.41

General Comments

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