INT75440

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Context Info
Confidence 0.38
First Reported 1998
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 4
Total Number 5
Disease Relevance 1.41
Pain Relevance 4.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Edn1) extracellular region (Edn1) cell-cell signaling (Edn1)
cytoplasm (Edn1)
Anatomy Link Frequency
smooth muscle 2
hearts 2
Edn1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 78 100.00 Very High Very High Very High
imagery 2 99.72 Very High Very High Very High
Morphine 36 95.96 Very High Very High Very High
anesthesia 1 93.60 High High
opioid receptor 4 90.32 High High
agonist 44 88.08 High High
Potency 6 86.32 High High
antagonist 90 76.24 Quite High
tolerance 10 75.00 Quite High
qutenza 28 74.36 Quite High
Disease Link Frequency Relevance Heat
Hypoxia 10 91.80 High High
Right Ventricular Hypertrophy 3 90.56 High High
Hypertension 8 81.68 Quite High
Neuroblastoma 2 75.00 Quite High
Pain 4 54.16 Quite High
Increased Venous Pressure Under Development 6 11.52 Low Low
Disease 8 5.00 Very Low Very Low Very Low
Cardiovascular Disease 6 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Blood samples were then collected for plasma ET-1 measurements, the rats killed, and their hearts dissected, dried, and weighed.
Regulation (collected) of ET-1 Binding (measurements) of in hearts
1) Confidence 0.38 Published 1998 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 9595473 Disease Relevance 1.15 Pain Relevance 0.17
We used imaging to study the effects of CGRP-receptor activation on binding of ET-1 to arterial smooth muscle ETA-receptors.
Regulation (effects) of ET-1 Binding (binding) of in smooth muscle associated with imagery and calcitonin gene-related peptide
2) Confidence 0.27 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2879375 Disease Relevance 0 Pain Relevance 0.59
Modulation of ET-1/ETA-receptor binding
Regulation (Modulation) of ET-1 Binding (binding) of
3) Confidence 0.27 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2879375 Disease Relevance 0 Pain Relevance 0.41
Acute and chronic exposure of cells to ET-1 did not affect changes in ET-1-induced GTP binding.
Neg (not) Regulation (changes) of ET-1-induced Binding (binding) of
4) Confidence 0.05 Published 2006 Journal Exp. Biol. Med. (Maywood) Section Abstract Doc Link 16741067 Disease Relevance 0.13 Pain Relevance 1.58
Acute and chronic exposure of cells to ET-1 did not affect changes in ET-1-induced GTP binding.
Neg (not) Regulation (affect) of ET-1-induced Binding (binding) of
5) Confidence 0.05 Published 2006 Journal Exp. Biol. Med. (Maywood) Section Abstract Doc Link 16741067 Disease Relevance 0.13 Pain Relevance 1.58

General Comments

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