INT75492

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Context Info
Confidence 0.40
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.84
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (LEPRE1) endoplasmic reticulum (LEPRE1) proteinaceous extracellular matrix (LEPRE1)
nucleus (LEPRE1) molecular_function (LEPRE1) cellular_component (LEPRE1)
Anatomy Link Frequency
leg 1
psoas major 1
LEPRE1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 7 99.84 Very High Very High Very High
Chronic pancreatitis 9 97.44 Very High Very High Very High
fibrosis 2 85.36 High High
backache 2 78.08 Quite High
Disease Link Frequency Relevance Heat
Pancreatitis 10 97.44 Very High Very High Very High
Fibrosis 2 85.36 High High
Low Back Pain 2 78.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We explain this decrease of OI activity by, respectively, decrease of gravity load, decrease of load from the psoas major muscles, and a substitute of self-bracing.
Negative_regulation (decrease) of OI in psoas major
1) Confidence 0.40 Published 1998 Journal J Electromyogr Kinesiol Section Abstract Doc Link 9779394 Disease Relevance 0.08 Pain Relevance 0.08
OI activity decreased significantly when (a) resting on one leg (the contralateral), as can be observed at bus stops, (b) tilting the pelvic backward and (c) applying a pelvic belt.
Negative_regulation (decreased) of OI in leg
2) Confidence 0.35 Published 1998 Journal J Electromyogr Kinesiol Section Abstract Doc Link 9779394 Disease Relevance 0.06 Pain Relevance 0.06
Prolyl hydroxylase and tissue inhibitor of metalloproteinase in pure pancreatic juice in patients with chronic pancreatitis.
Negative_regulation (inhibitor) of Prolyl hydroxylase associated with metalloproteinase and chronic pancreatitis
3) Confidence 0.21 Published 1998 Journal Pancreas Section Title Doc Link 9598809 Disease Relevance 0.70 Pain Relevance 0.82

General Comments

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