INT75557

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.52
First Reported 1998
Last Reported 2010
Negated 3
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.96
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Jund) nucleus (Jund) DNA binding (Jund)
protein complex (Jund)
Anatomy Link Frequency
THP-1 1
PGE2 1
Jund (Rattus norvegicus)
Pain Link Frequency Relevance Heat
conotoxin 1 87.36 High High
beta blocker 1 84.28 Quite High
dexamethasone 1 78.48 Quite High
Hippocampus 2 75.00 Quite High
Enkephalin 5 25.00 Low Low
ischemia 8 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 1 96.48 Very High Very High Very High
Acute Monocytic Leukemia 1 94.52 High High
Cancer 5 87.76 High High
Myocardial Infarction 4 86.28 High High
Coronary Artery Disease 4 82.52 Quite High
Bordatella Infection 2 81.20 Quite High
Vibrio Infection 2 75.00 Quite High
Cv Unclassified Under Development 8 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The pre-administration with L-NAME further increased KA-induced c-jun and c-fos mRNA levels in addition to their protein product levels, although the pre-treatment with L-NAME did not affect KA-induced FosB, Fra-2, JunB, and JunD protein levels at 6 h after treatment.
Neg (not) Regulation (affect) of JunD
1) Confidence 0.52 Published 1998 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 9602069 Disease Relevance 0 Pain Relevance 0.07
The treatment with CTX, but not PTX, increased c-Fos and Fra-2 protein levels as well as AP-1, CRE, or ENKCRE-2 DNA binding activity, but neither toxin affected Fra-1, c-Jun, JunB, and JunD protein levels.
Neg (neither) Regulation (affected) of JunD
2) Confidence 0.42 Published 2001 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 11295234 Disease Relevance 0.30 Pain Relevance 0.04
However, c-Jun, JunB, and JunD protein levels were not affected by PGE2.
Neg (not) Regulation (affected) of JunD in PGE2
3) Confidence 0.36 Published 1998 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 9757037 Disease Relevance 0 Pain Relevance 0.04
Resveratrol decreases the levels of miR-155 in THP-1 and modulating JunB and JunD, key regulators in carcinogenesis [31].
Regulation (modulating) of JunD in THP-1
4) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3009730 Disease Relevance 0.66 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox