INT75626

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Context Info
Confidence 0.50
First Reported 1998
Last Reported 2006
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.52
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (Dst) endoplasmic reticulum (Dst) cytoplasm (Dst)
cell motility (Dst) cell adhesion (Dst) cytoplasmic membrane-bounded vesicle (Dst)
Anatomy Link Frequency
neuronal 1
Dst (Mus musculus)
Pain Link Frequency Relevance Heat
Hsan 2 99.44 Very High Very High Very High
Root ganglion neuron 1 95.24 Very High Very High Very High
Spinal cord 2 92.28 High High
Disease Link Frequency Relevance Heat
Bullous Skin Disease 2 100.00 Very High Very High Very High
Hereditary Sensory And Autonomic Neuropathies 2 99.44 Very High Very High Very High
Dystonia 3 96.68 Very High Very High Very High
Ganglion Cysts 1 94.92 High High
Neurodegenerative Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results demonstrate that dystonin is essential for maintaining neuronal cytoskeleton integrity but is not required for establishing neuronal morphology.
Neg (not) Positive_regulation (required) of dystonin in neuronal
1) Confidence 0.50 Published 1998 Journal Mol. Cell. Neurosci. Section Abstract Doc Link 9604204 Disease Relevance 0.15 Pain Relevance 0.13
A defective bullous pemphigoid antigen 1 (BPAG1) gene is responsible for this mutation.
Positive_regulation (responsible) of bullous pemphigoid antigen 1 associated with bullous skin disease
2) Confidence 0.39 Published 2006 Journal J. Neuropathol. Exp. Neurol. Section Abstract Doc Link 16691115 Disease Relevance 0.37 Pain Relevance 0.10

General Comments

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